Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes (Q28369082)

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Language	Label	Description	Also known as
English	Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes	scientific article

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scholarly article

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Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes (English)

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author name string

S D Malley

1

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J M Grange

2

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F Hamedi-Sangsari

3

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J R Vila

4

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language of work or name

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publication date

8 November 1994

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Proceedings of the National Academy of Sciences of the United States of America

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91

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23

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11017-21

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HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

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20 March 2017

Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication

1 reference

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Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis

1 reference

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Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

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Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

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20 March 2017

Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1

1 reference

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20 March 2017

HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure

1 reference

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Molecular targets for AIDS therapy

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Therapy for human immunodeficiency virus infection

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Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells

1 reference

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Interactions between deoxyribonucleotide and DNA synthesis

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Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).

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Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro

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HIV-1 replication is controlled at the level of T cell activation and proviral integration

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Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

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An overview of the clinical experience with hydroxyurea

1 reference

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29 September 2017

Mechanism of action of hydroxyurea

1 reference

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Antiretroviral therapy: strategies beyond single-agent reverse transcriptase inhibition

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HIV inhibitors targeted at the reverse transcriptase

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Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle

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Intracellular metabolism of 3'-azidothymidine in isolated human peripheral blood mononuclear cells

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Identifiers

10.1073/PNAS.91.23.11017

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1994PNAS...9111017M

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PMC publication ID

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