A binding site model and structure-activity relationships for the rat A3 adenosine receptor (Q28369257)

2

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C Gallo-Rodriguez

3

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N Melman

4

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M E Olah

5

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A P IJzerman

6

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G L Stiles

7

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K A Jacobson

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

8

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language of work or name

English

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publication date

June 1994

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published in

Molecular Pharmacology

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volume

45

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issue

6

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page(s)

1101-11

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cites work

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Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor

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This is not a G protein-coupled receptor.

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Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions

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Structure and function of A1 adenosine receptors

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Molecular cloning of a novel putative G-protein coupled receptor expressed during rat spermiogenesis

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Cloning, expression, and characterization of the unique bovine A1 adenosine receptor. Studies on the ligand binding site by site-directed mutagenesis

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Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists

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Adenosine A3 receptors mediate hypotension in the angiotensin II-supported circulation of the pithed rat.

2 June 2018

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The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells

2 June 2018

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Adenosine receptor activation in human fibroblasts: nucleoside agonists and antagonists

2 June 2018

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Adenosine receptor agonists: synthesis and biological evaluation of 1-deaza analogues of adenosine derivatives

2 June 2018

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Structure-activity profile of a series of novel triazoloquinazoline adenosine antagonists

2 June 2018

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2',3'-Dideoxy-N6-cyclohexyladenosine: an adenosine derivative with antagonist properties at adenosine receptors.

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Chemical modification of A1 adenosine receptors in rat brain membranes. Evidence for histidine in different domains of the ligand binding site

2 June 2018

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N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors.

2 June 2018

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Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes

2 June 2018

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The A1 adenosine receptor. Identification of the binding subunit by photoaffinity cross-linking.

2 June 2018

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4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.

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Imidazodiazepinediones: a new class of adenosine receptor antagonists

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N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.

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Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors

2 June 2018

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Receptor binding profiles of amiloride analogues provide no evidence for a link between receptors and the Na+/H+ exchanger, but indicate a common structure on receptor proteins

2 June 2018

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Agonist activity of 2- and 5'-substituted adenosine analogs and their N6-cycloalkyl derivatives at A1- and A2-adenosine receptors coupled to adenylate cyclase

2 June 2018

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Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor.

2 June 2018

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Molecular modeling of adenosine receptors. The ligand binding site on the rat adenosine A2A receptor

2 June 2018

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12 December 2020

Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors

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12 December 2020

A steric and electrostatic comparison of three models for the agonist/antagonist binding site on the adenosine A1 receptor

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12 December 2020

Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines

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12 December 2020

Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists

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12 December 2020

Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines

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12 December 2020