Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS 4071. (Q28369317)

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7 December 2019

title

Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS 4071 (English)

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7 December 2019

author name string

C Y Tai

1

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7 December 2019

P A Escarpe

2

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7 December 2019

R W Sidwell

3

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7 December 2019

M A Williams

4

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7 December 2019

W Lew

5

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H Wu

6

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C U Kim

7

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7 December 2019

D B Mendel

8

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7 December 2019

language of work or name

English

0 references

publication date

1 December 1998

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Antimicrobial Agents and Chemotherapy

7 December 2019

published in

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7 December 2019

volume

42

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issue

12

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7 December 2019

page(s)

3234-3241

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Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS 4071 protects mice and ferrets against influenza infection

7 December 2019

cites work

1 reference

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4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro

20 March 2017

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20 March 2017

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Inhibition of influenza virus replication in mice by GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is consistent with extracellular activity of viral neuraminidase (sialidase)

20 March 2017

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20 March 2017

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20 March 2017

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The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid

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The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

20 March 2017

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Rational design of potent sialidase-based inhibitors of influenza virus replication

7 April 2017

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Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity

7 April 2017

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Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor

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Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors

29 September 2017

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Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections. GG167 Influenza Study Group.

29 September 2017

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Adaptation of egg-grown and transfectant influenza viruses for growth in mammalian cells: selection of hemagglutinin mutants with elevated pH of membrane fusion

29 September 2017

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Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en.

29 September 2017

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Mutation in the influenza virus neuraminidase gene resulting in decreased sensitivity to the neuraminidase inhibitor 4-guanidino-Neu5Ac2en leads to instability of the enzyme

29 September 2017

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Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en.

29 September 2017

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Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en

29 September 2017

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GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is a potent inhibitor of influenza virus in ferrets

29 September 2017

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Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en

29 September 2017

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Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Inhibition of the growth of influenza viruses in vitro by 4-guanidino-2,4-dideoxy-N-acetylneuraminic acid

2 June 2018

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2 June 2018

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Fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl-alpha-D-N-acetylneuraminate) substrate

2 June 2018

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Mucins and mucoids in relation to influenza virus action; inhibition by purified mucoid of infection and haemagglutination with the virus strain WSE.

2 June 2018

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A single sequence change destabilizes the influenza virus neuraminidase tetramer

27 November 2018

1 reference

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Selection of influenza A and B viruses for resistance to 4-guanidino-Neu5Ac2en in cell culture

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9835519

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.42.12.3234

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9835519%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

7 December 2019

3040002

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3040002

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9835519%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

PubMed publication ID

9835519

1 reference