Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT1 and 5-HT2 receptors (Q28369500)

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S Brough

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M C Coldwell

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T Gager

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M Ho

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A J Hunter

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J Jerman

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D N Middlemiss

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G J Riley

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A M Brown

British Journal of Pharmacology

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language of work or name

English

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publication date

December 1998

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published in

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volume

125

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issue

7

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page(s)

1413-20

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cites work

Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease

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Action of agonists and antagonists at muscarinic receptors present on ileum and atria in vitro

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Relative affinities of drugs acting at cholinoceptors in displacing agonist and antagonist radioligands: the NMS/Oxo-M ratio as an index of efficacy at cortical muscarinic receptors

21 January 2018

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In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties

21 January 2018

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Pharmacological characterization of acetylcholine-stimulated [35S]-GTP gamma S binding mediated by human muscarinic m1-m4 receptors: antagonist studies

21 January 2018

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Novel persistent activation of muscarinic M1 receptors by xanomeline

21 January 2018

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7 January 2021

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

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The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from Chinese hamster ovary-m1 cells

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7 January 2021

Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

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7 January 2021

Distinct kinetic binding properties of N-[3H]-methylscopolamine afford differential labeling and localization of M1, M2, and M3 muscarinic receptor subtypes in primate brain

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SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

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Heterogeneity and selectivity of the degeneration of cholinergic neurons in the basal forebrain of patients with Alzheimer's disease

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Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies

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Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation.

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Stimulation of guanosine 5'-O-(3-[35S] thiotriphosphate) binding by cholinergic muscarinic receptors in membranes of rat olfactory bulb.

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Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

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7 January 2021

Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3-(1,2,5-thiadiazolyl)-1,2,5,6-tetrahydro-1-methylpyridines

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7 January 2021

SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity

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GR127935 acts as a partial agonist at recombinant human 5-HT1D alpha and 5-HT1D beta receptors

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Role of ganglionic M-1 and M-2 receptors in the neuronal control of the cardiovascular system of the normotensive rat as determined with pilocarpine

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7 January 2021

release_r32iczpan5hxjagi6ojagkpgky

Identifiers

DOI

10.1038/SJ.BJP.0702201

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Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/r32iczpan5hxjagi6ojagkpgky

24 November 2022