Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor (Q28369516)

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25 October 2019

title

Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor (English)

1 reference

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25 October 2019

author name string

D D Ho

1

1 reference

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25 October 2019

T Toyoshima

2

1 reference

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25 October 2019

H Mo

3

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25 October 2019

D J Kempf

4

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25 October 2019

D Norbeck

5

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25 October 2019

C M Chen

6

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25 October 2019

N E Wideburg

7

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25 October 2019

S K Burt

8

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25 October 2019

J W Erickson

9

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25 October 2019

M K Singh

10

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25 October 2019

language of work or name

English

0 references

publication date

1 March 1994

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25 October 2019

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25 October 2019

volume

68

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25 October 2019

issue

3

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25 October 2019

page(s)

2016-2020

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In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease

25 October 2019

cites work

1 reference

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20 March 2017

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X-ray analysis of HIV-1 proteinase at 2.7 A resolution confirms structural homology among retroviral enzymes

20 March 2017

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Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

20 March 2017

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Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

20 March 2017

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Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

20 March 2017

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HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

20 March 2017

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A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation

20 March 2017

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Structure-based, C2 symmetric inhibitors of HIV protease

20 March 2017

1 reference

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Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease

20 March 2017

1 reference

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Rational design of peptide-based HIV proteinase inhibitors

20 March 2017

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Antiviral and pharmacokinetic properties of C2 symmetric inhibitors of the human immunodeficiency virus type 1 protease

20 March 2017

1 reference

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Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture

20 March 2017

1 reference

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Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase

20 March 2017

1 reference

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Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture

20 March 2017

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Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors

20 March 2017

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Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl substituents: X-ray crystal structure assisted design

20 March 2017

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Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine

20 March 2017

1 reference

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Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2',3'-dideoxycytidine

20 March 2017

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Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

20 March 2017

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Present status and future prospects for HIV therapies

7 April 2017

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29 September 2017

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29 September 2017

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PCR amplification of HIV-1 proteinase sequences directly from lab isolates allows determination of five conserved domains

29 September 2017

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Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing -hydrophobic*hydrophobic- or -aromatic*pro- cleavage sites

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