Mitochondrial damage by the "pro-oxidant" peroxisomal proliferator clofibrate (Q28376701)

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Q T Li

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K P Wong

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C N Ong

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B Halliwell

Free Radical Biology and Medicine

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language of work or name

English

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publication date

November 1999

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published in

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volume

27

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issue

9-10

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page(s)

1095-102

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cites work

Peroxisome proliferation and hepatocarcinogenesis

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7 January 2021

Effect of the peroxisome proliferator ciprofibrate on lipid peroxidation and 8-hydroxydeoxyguanosine formation in transgenic mice with elevated hepatic catalase activity

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7 January 2021

Induction of peroxisomes by treatment with perfluorooctanoate does not increase rates of H2O2 production in intact liver

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7 January 2021

Lack of DNA damage or lipid peroxidation measured in vivo in the rat liver following treatment with peroxisomal proliferators

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7 January 2021

Evidence against peroxisome proliferation-induced hepatic oxidative damage

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7 January 2021

Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids

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7 January 2021

Establishing the significance and optimal intake of dietary antioxidants: the biomarker concept

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7 January 2021

The isoprostanes: unique bioactive products of lipid peroxidation

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7 January 2021

Thyromimetic action of the peroxisome proliferators clofibrate, perfluorooctanoic acid, and acetylsalicylic acid includes changes in mRNA levels for certain genes involved in mitochondrial biogenesis

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7 January 2021

Effects of hypolipidaemics cetaben and clofibrate on mitochondrial and peroxisomal enzymes of rat liver

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7 January 2021

The nongenotoxic hepatocarcinogen Wy-14,643 is an uncoupler of oxidative phosphorylation in vivo

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7 January 2021

Estimation of peroxisomal beta-oxidation in rat heart by a direct assay of acyl-CoA oxidase

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7 January 2021

Structural analysis of ATP synthase from bovine heart mitochondria.

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7 January 2021

Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: relationship to mitochondrial alterations

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7 January 2021

Study of protein carbonyls in subcellular fractions isolated from liver and spleen of old and gamma-irradiated rats

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7 January 2021

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

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7 January 2021

Effect of age-related lipid peroxidation on membrane fluidity and phospholipase A2: modulation by dietary restriction

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7 January 2021

Alterations in mitochondrial membrane fluidity by lipid peroxidation products

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7 January 2021

A simple microassay for inorganic phosphate, II

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Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo

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Improvements in the analytical method for 8-hydroxydeoxyguanosine in nuclear DNA

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A rapid alkaline extraction procedure for screening recombinant plasmid DNA

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Rapid isolation of animal mitochondrial DNA by alkaline extraction

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7 January 2021

Increased oxidative damage to mitochondrial DNA following chronic ethanol consumption

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7 January 2021

Detection of oxidative DNA damage in human sperm and the association with cigarette smoking.

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7 January 2021

A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease.

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7 January 2021

Brain synaptosomal aging: free radicals and membrane fluidity

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7 January 2021

Oxidative Decay of DNA

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Oxidative damage to mitochondrial DNA and its relationship to ageing

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7 January 2021

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

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7 January 2021

Lack of induction of hepatic DNA damage on long-term administration of peroxisome proliferators in male F-344 rats

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7 January 2021

Increased 8-hydroxydeoxyguanosine in hepatic DNA of rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid

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7 January 2021

Formation of 8-oxodeoxyguanosine in liver DNA and hepatic injury by peroxisome proliferator clofibrate and perfluorodecanoic acid in rats

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7 January 2021

Can oxidative DNA damage be used as a biomarker of cancer risk in humans? Problems, resolutions and preliminary results from nutritional supplementation studies

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7 January 2021

Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry

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7 January 2021

Protein oxidation associated with aging is reduced by dietary restriction of protein or calories

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7 January 2021

Protein oxidation and aging

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7 January 2021

Carbonyl assays for determination of oxidatively modified proteins.

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7 January 2021

Mitochondrial oxidative damage, hydrogen peroxide release, and aging.

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7 January 2021

Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

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7 January 2021

Hg(II)-induced renal cytotoxicity: in vitro and in vivo implications for the bioenergetic and oxidative status of mitochondria

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7 January 2021

Inhibition of mitochondrial respiration and oxygen-dependent hepatotoxicity by six structurally dissimilar peroxisomal proliferating agents

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7 January 2021

Effects of clofibrate, in vitro, on mitochondrial respiration and oxidative phosphorylation

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7 January 2021

An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease

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7 January 2021

10.1016/S0891-5849(99)00143-4

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

10569642

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Consolidated OpenCitations Corpus – April 2017