A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor (Q28379187)

1

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K Grovit-Ferbas

2

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M P Sharron

3

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S H Mao

4

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M B Goetz

5

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E S Daar

6

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R W Doms

7

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W A O'Brien

Journal of Experimental Medicine

8

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language of work or name

English

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publication date

20 October 1997

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published in

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volume

186

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page(s)

1395-400

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issue

8

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cites work

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A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

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Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

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HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor

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Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains

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