Anti-Pneumocystis activities of aromatic diamidoxime prodrugs (Q28379412)

2 July 2017

title

Anti-Pneumocystis activities of aromatic diamidoxime prodrugs (English)

1 reference

2 July 2017

J E Hall

1

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2 July 2017

J E Kerrigan

2

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2 July 2017

K Ramachandran

3

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2 July 2017

B C Bender

4

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2 July 2017

J P Stanko

5

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2 July 2017

S K Jones

6

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2 July 2017

D A Patrick

7

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2 July 2017

R R Tidwell

8

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2 July 2017

language of work or name

English

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publication date

1 March 1998

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Antimicrobial Agents and Chemotherapy

2 July 2017

published in

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2 July 2017

volume

42

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2 July 2017

issue

3

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2 July 2017

page(s)

666-674

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Activity of cationically substituted bis-benzimidazoles against experimental Pneumocystis carinii pneumonia

2 July 2017

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20 March 2017

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Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia

20 March 2017

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Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis

20 March 2017

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Inhibition of Cryptosporidium parvum in neonatal Hsd:(ICR)BR Swiss miceby polyether ionophores and aromatic amidines

20 March 2017

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New aromatic diamidines with central alpha-oxyalkane or alpha, omega-dioxyalkane chains. Structure-activity relationships for the inhibition of trypsin, pancreatic kallikrein, and thrombin and for the inhibition of the overall coagulation process

20 March 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

20 March 2017

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A new family of tuberculostatic compounds: the amidoximes

7 April 2017

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Metabolism is an important route of pentamidine elimination in the rat: disposition of 14C-pentamidine and identification of metabolites in urine using liquid chromatography-tandem mass spectrometry

29 September 2017

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Suppression of local and systemic responses in streptococcal cell wall-induced acute inflammation of the air pouch by cyclosporine A. Comparison with the effects of two anti-inflammatory bis-benzimidazoles.

29 September 2017

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Structure-activity studies of dicationically substituted bis-benzimidazoles against Giardia lamblia: correlation of antigiardial activity with DNA binding affinity and giardial topoisomerase II inhibition

29 September 2017

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Dicationic diarylfurans as anti-Pneumocystis carinii agents

29 September 2017

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Inhibition of respiratory syncytial virus-host cell interactions by mono- and diamidines

29 September 2017

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Present status of chemotherapy and chemopropylaxis of human trypanosomiasis in the Eastern Hemisphere

29 September 2017

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Suppression of respiratory syncytial virus infection in cotton rats by bis(5-amidino-2-benzimidazolyl)methane

29 September 2017

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Pentamidine isethionate in the treatment of Pneumocystis carinii pneumonia

29 September 2017

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Pentamidine isethionate. A review of its antiprotozoal activity, pharmacokinetic properties and therapeutic use in Pneumocystis carinii pneumonia

29 September 2017

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Protease inhibitors suppress the in vitro and in vivo replication of rotavirus

29 September 2017

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Sequential events in the pathogenesis of streptococcal cell wall-induced arthritis and their modulation by bis(5-amidino-2-benzimidazolyl)methane (BABIM).

29 September 2017

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Metabolic N-hydroxylation of pentamidine in vitro

29 September 2017

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Activity of pentamidine and pentamidine analogs against Toxoplasma gondii in cell cultures

29 September 2017

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Structure-activity relationships of pentamidine analogs against Giardia lamblia and correlation of antigiardial activity with DNA-binding affinity

29 September 2017

1 reference

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Streptococcal cell wall-induced systemic disease. Beneficial effects of trans-bis(5-amidino-2-benzimidazolyl)ethene, a novel, macrophage-directed anti-inflammatory agent

29 September 2017

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Primary and secondary metabolism of pentamidine by rats

29 September 2017

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Amidino-substituted aromatic heterocycles as probes of the specificity pocket of trypsin-like proteases

29 September 2017

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Inhibitory effect of amidino-substituted heterocyclic compounds on the amidase activity of plasmin and of high and low molecular weight urokinase and on urokinase-induced plasminogen activation

29 September 2017

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Inhibition of respiratory syncytial virus by bis(5-amidino-2-benzimidazolyl)methane

2 June 2018

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A rapid staining procedure for Pneumocystis carinii.

2 June 2018

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Amidoximes of pentamidine: synthesis, trypanocidal and leishmanicidal activity

2 June 2018

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Metabolic N-hydroxylation of diminazene in vitro

2 June 2018

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Synthesis of dicationic diaryltriazines nucleic acid binding agents

2 June 2018

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N-hydroxylation of the antiprotozoal drug pentamidine catalyzed by rabbit liver cytochrome P-450 2C3 or human liver microsomes, microsomal retroreduction, and further oxidative transformation of the formed amidoximes. Possible relationship to the bi

27 November 2018

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Experimental chemotherapy of typhus Anti-rickettsial action of p -sulphonamidobenzamidine and related compounds

27 November 2018

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12 December 2020

Hydroxylation of pentamidine by rat liver microsomes

1 reference

12 December 2020

[New research on the interrelations of chemical structure, antibacterial & antifungal activity & toxicity of the N-substituted dithiocarbamic acid ester series]

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12 December 2020

Specific inhibition of platelet agglutination and aggregation by aromatic amidino compounds

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12 December 2020

Orally active fibrinogen receptor antagonists. 2. Amidoximes as prodrugs of amidines

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12 December 2020

Novel bis(benzamidino) compounds with an aromatic central link. Inhibitors of thrombin, pancreatic kallikrein, trypsin, and complement

1 reference

12 December 2020

Suppression of streptococcal cell wall-induced arthritis by a potent protease inhibitor, bis(5-amidino-2-benzimidazolyl)methane

1 reference

12 December 2020

Reduction of amidoxime derivatives to pentamidine in vivo

1 reference

12 December 2020

Identifiers

PMC publication ID

105515

0 references

1 reference