NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration (Q28384823)

1

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Tao Ma

2

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Shiyong Diao

3

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Xue Zhang

4

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Yaomin Chen

5

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Janet Hsu

6

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Stuart A Lipton

7

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Huaxi Xu

9

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Francesca-Fang Liao

Molecular Neurodegeneration

10

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language of work or name

English

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publication date

10 November 2010

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published in

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volume

5

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page(s)

49

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issue

1

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exact match

https://scigraph.springernature.com/pub.10.1186/1750-1326-5-49

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cites work

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Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

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Role of S-nitrosylation in apoptosis resistance and carcinogenesis

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Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities

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NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

20 March 2017

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Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse

20 March 2017

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Phosphorylation of the PTEN tail regulates protein stability and function

20 March 2017

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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

20 March 2017

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

20 March 2017

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P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

20 March 2017

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Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

20 March 2017

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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

20 March 2017

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Ischemic Postconditioning as a Novel Avenue to Protect against Brain Injury after Stroke

20 March 2017

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A role for nuclear PTEN in neuronal differentiation.

7 April 2017

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Reversible inactivation of the tumor suppressor PTEN by H2O2

7 April 2017

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Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

7 April 2017

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Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

7 April 2017

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Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc

29 September 2017

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Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

29 September 2017

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CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia

29 September 2017

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Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling.

29 September 2017

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Protein S-nitrosylation in health and disease: a current perspective

29 September 2017

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Nitric oxide in cell survival: a janus molecule

29 September 2017

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Phosphorylation keeps PTEN phosphatase closed for business

29 September 2017

1 reference

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Post-translational regulation of PTEN.

29 September 2017

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Nitric oxide-dependent proteasomal degradation of cytochrome P450 2B proteins

29 September 2017

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Phosphatase PTEN in neuronal injury and brain disorders

29 September 2017

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PTEN is destabilized by phosphorylation on Thr366.

29 September 2017

1 reference

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PTEN, the Achilles' heel of myocardial ischaemia/reperfusion injury?

29 September 2017

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GSK-3 is essential in the pathogenesis of Alzheimer's disease.

29 September 2017

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Cerebral preconditioning and ischaemic tolerance

29 September 2017

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PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury

29 September 2017

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Redox regulation of PTEN by S-nitrosothiols

29 September 2017

1 reference

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Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

29 September 2017

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Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

29 September 2017

1 reference

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S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway

29 September 2017

1 reference

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Redox regulation of PI 3-kinase signalling via inactivation of PTEN

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex

29 September 2017

1 reference

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Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Tumor-suppressor PTEN affects tau phosphorylation, aggregation, and binding to microtubules

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

PTEN activity is modulated during ischemia and reperfusion: involvement in the induction and decay of preconditioning

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

PTEN levels in Alzheimer's disease medial temporal cortex

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Role of protein kinase B in Alzheimer's neurofibrillary pathology

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

The biotin switch method for the detection of S-nitrosylated proteins

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992530

27 November 2018

Identifiers

DOI

10.1186/1750-1326-5-49

1 reference

Dimensions Publication ID

2880813

1029865290

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2880813

1 reference

1 reference

1 reference