Impacts of environmental toxicants on male reproductive dysfunction (Q28388373)

Trends in Pharmacological Sciences

Europe PubMed Central

title

Impacts of environmental toxicants on male reproductive dysfunction (English)

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C Yan Cheng

2

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author name string

Elissa W P Wong

series ordinal

1

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language of work or name

English

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publication date

May 2011

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published in

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volume

32

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issue

5

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page(s)

290-9

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cites work

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Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?

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Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

20 March 2017

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Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress

20 March 2017

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Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

20 March 2017

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Restricted Arp3 expression in the testis prevents blood-testis barrier disruption during junction restructuring at spermatogenesis

20 March 2017

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Connexin 43 and plakophilin-2 as a protein complex that regulates blood-testis barrier dynamics

20 March 2017

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Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

20 March 2017

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Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis

20 March 2017

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Interleukin 1 alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat

20 March 2017

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Extracellular signal-regulated kinase activation during renal ischemia/reperfusion mediates focal adhesion dissolution and renal injury

20 March 2017

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Differential interactions between transforming growth factor-beta3/TbetaR1, TAB1, and CD2AP disrupt blood-testis barrier and Sertoli-germ cell adhesion

20 March 2017

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Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes

20 March 2017

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Epigenetic transgenerational actions of endocrine disruptors and male fertility

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Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure

7 April 2017

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Connexin 43 is critical to maintain the homeostasis of the blood-testis barrier via its effects on tight junction reassembly

7 April 2017

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Cadmium suppresses the proliferation of piglet Sertoli cells and causes their DNA damage, cell apoptosis and aberrant ultrastructure

29 September 2017

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Roles of dioxins and heavy metals in cancer and neurological diseases using ROS-mediated mechanisms

29 September 2017

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The dual kinase complex FAK-Src as a promising therapeutic target in cancer

29 September 2017

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Cadmium ions induce monocytic production of tumor necrosis factor-alpha by inhibiting mitogen activated protein kinase dephosphorylation

29 September 2017

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Oocyte activation, phospholipase C zeta and human infertility

29 September 2017

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A local autocrine axis in the testes that regulates spermatogenesis

29 September 2017

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Regulation of blood-testis barrier dynamics by TGF-beta3 is a Cdc42-dependent protein trafficking event

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Oestrogens and spermatogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Hydrogen peroxide activates focal adhesion kinase and c-Src by a phosphatidylinositol 3 kinase-dependent mechanism and promotes cell migration in Caco-2 cell monolayers

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Adverse effects of low level heavy metal exposure on male reproductive function

29 September 2017

1 reference

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Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells.

29 September 2017

1 reference

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Epigenetic transgenerational actions of environmental factors in disease etiology

29 September 2017

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Nongenomic signaling pathways of estrogen toxicity.

29 September 2017

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29 September 2017

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Polarity proteins and cell-cell interactions in the testis

29 September 2017

1 reference

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Src kinases as therapeutic targets for cancer

29 September 2017

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Epigenetic transgenerational effects of endocrine disruptors on male reproduction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Low doses of bisphenol A promote human seminoma cell proliferation by activating PKA and PKG via a membrane G-protein-coupled estrogen receptor

29 September 2017

1 reference

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Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling

29 September 2017

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14-3-3 Protein regulates cell adhesion in the seminiferous epithelium of rat testes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Changes in MAPK pathway in neonatal and adult testis following fetal estrogen exposure and effects on rat testicular cells

29 September 2017

1 reference

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Membrane-initiated actions of estrogen on the endothelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Focal adhesion kinase is a blood-testis barrier regulator

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

The role of Mitogen activated protein kinase (MAPK) in sperm functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Regulators of endothelial and epithelial barrier integrity and function in acute lung injury

29 September 2017

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Role of antioxidants in the treatment of male infertility

29 September 2017

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Mitogen-activated protein kinases in male reproductive function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Cadmium-induced testicular injury

29 September 2017

1 reference

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Role of oxidative stress in cadmium toxicity and carcinogenesis

29 September 2017

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An occludin-focal adhesion kinase protein complex at the blood-testis barrier: a study using the cadmium model

29 September 2017

1 reference

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TGF-beta3 and TNFalpha perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: a new concept of BTB regulation during spermatogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Blood-brain barrier tight junction permeability and ischemic stroke

29 September 2017

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Src and focal adhesion kinase as therapeutic targets in cancer

29 September 2017

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Cadmium specifically induces MKP-1 expression via the glutathione depletion-mediated p38 MAPK activation in C6 glioma cells

29 September 2017

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Oxidative stress: a common factor in testicular dysfunction

29 September 2017

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Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte cocultures.

29 September 2017

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Mechanisms of asymmetric cell division: flies and worms pave the way.

29 September 2017

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TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia

29 September 2017

1 reference

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Science linking environmental contaminant exposures with fertility and reproductive health impacts in the adult male

29 September 2017

1 reference

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Oxidative stress and male infertility--a clinical perspective

29 September 2017

1 reference

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Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Polarity complex proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Rapid activation of c-Src kinase by dioxin is mediated by the Cdc37-HSP90 complex as part of Ah receptor signaling in MCF10A cells

29 September 2017

1 reference

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Inflammatory mediators exert toxic effects of oxidative stress on human spermatozoa.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling

29 September 2017

1 reference

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Requirements for proximal tubule epithelial cell detachment in response to ischemia: role of oxidative stress.

29 September 2017

1 reference

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Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt.

29 September 2017

1 reference

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Best practice policies for male infertility

29 September 2017

1 reference

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Relative impact of oxidative stress on male reproductive function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor alpha and estrogen receptor beta

29 September 2017

1 reference

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Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

The interplay of collagen IV, tumor necrosis factor-alpha, gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloproteases-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis

2 June 2018

1 reference

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Treatment of rats during pubertal development with 2,3,7,8-tetrachlorodibenzo-p-dioxin alters both signaling kinase activities and epidermal growth factor receptor binding in the testis and the motility and acrosomal reaction of sperm

2 June 2018

1 reference

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Molecular mechanisms regulating dissociation of cell-cell junction of epithelial cells by oxidative stress.

2 June 2018

1 reference

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Urinary metabolites of polycyclic aromatic hydrocarbons in relation to idiopathic male infertility

27 November 2018

1 reference

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Low dose of 2,3,7,8 tetrachlorodibenzo-p-dioxin induces testicular oxidative stress in adult rats under the influence of corticosterone

27 November 2018

1 reference

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Drosophila Cip4 and WASp define a branch of the Cdc42-Par6-aPKC pathway regulating E-cadherin endocytosis.

27 November 2018

1 reference

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Enhanced TGF-beta1 is involved in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced oxidative stress in C57BL/6 mouse testis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Motorcycle exhaust induces reproductive toxicity and testicular interleukin-6 in male rats

27 November 2018

1 reference

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Effect of vitamins C and E on spermatogenesis in mice exposed to cadmium

27 November 2018

1 reference

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Environmental toxicant-induced germ cell apoptosis in the human fetal testis.

27 November 2018

1 reference

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Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic

27 November 2018

1 reference

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Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3.

27 November 2018

1 reference

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Redox regulation of 4-hydroxy-2-nonenal-mediated endothelial barrier dysfunction by focal adhesion, adherens, and tight junction proteins.

27 November 2018

1 reference

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Tumor necrosis factor {alpha} reversibly disrupts the blood-testis barrier and impairs Sertoli-germ cell adhesion in the seminiferous epithelium of adult rat testes.

27 November 2018

1 reference

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Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Renal ischemia/reperfusion injury: functional tissue preservation by anti-activated {beta}1 integrin therapy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Exposure to bisphenol A during embryonic/fetal life and infancy increases oxidative injury and causes underdevelopment of the brain and testis in mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Regulation of blood-testis barrier dynamics: an in vivo study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Role of Phosphatidylinositol 3-Kinase in Oxidative Stress-induced Disruption of Tight Junctions

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Mediation of cadmium‐induced oxidative damage and glucose‐6‐phosphate dehydrogenase expression through glutathione depletion

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Adhering Junction Dynamics in the Testis Are Regulated by an Interplay of β1-Integrin and Focal Adhesion Complex-Associated Proteins

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

TGF-beta3 regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Transforming growth factor beta3 regulates the dynamics of Sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Expression of kinase-inactive c-Src delays oxidative stress-induced disassembly and accelerates calcium-mediated reassembly of tight junctions in the Caco-2 cell monolayer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Effects of vitamin E on reactive oxygen species-mediated 2,3,7,8-tetrachlorodi-benzo-p-dioxin toxicity in rat testis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

Regional differences in waiting time to pregnancy: pregnancy-based surveys from Denmark, France, Germany, Italy and Sweden. The European Infertility and Subfecundity Study Group.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090518

The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility

27 November 2018

1 reference

12 December 2020

A kinetic model of cadmium metabolism in the human being

1 reference

12 December 2020

Epidemiology and aetiology of male infertility

1 reference

12 December 2020

A complex containing alpha6beta1-integrin and phosphorylated focal adhesion kinase between Sertoli cells and elongated spermatids during spermatid release from the seminiferous epithelium

1 reference

12 December 2020

Homocysteine-induced myofibroblast differentiation in mouse aortic endothelial cells

1 reference

12 December 2020

Homocysteine-induced biochemical stress predisposes to cytoskeletal remodeling in stretched endothelial cells

1 reference

12 December 2020

1 reference

12 December 2020

Exposing p120 catenin's most intimate affair

1 reference

12 December 2020