The dynamics of autism spectrum disorders: how neurotoxic compounds and neurotransmitters interact (Q28388719)

13 March 2019

9 September 2019

2 October 2019

7 November 2019

30 May 2020

on focus list of Wikimedia project

24 August 2020

copyright status

copyrighted

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cites work

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Does perinatal exposure to endocrine disruptors induce autism spectrum and attention deficit hyperactivity disorders? Review

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Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

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Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood

20 March 2017

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Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children

20 March 2017

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Prevalence of autism-spectrum conditions: UK school-based population study

20 March 2017

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Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

20 March 2017

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Common genetic variants on 5p14.1 associate with autism spectrum disorders

20 March 2017

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The rise in autism and the role of age at diagnosis

20 March 2017

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Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central Valley

20 March 2017

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Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats

20 March 2017

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Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children

20 March 2017

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Developmental neurotoxicity of industrial chemicals

20 March 2017

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Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure

20 March 2017

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Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors

20 March 2017

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Chemical contaminants in breast milk and their impacts on children's health: an overview

20 March 2017

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Acetylcholinesterase--new roles for an old actor

20 March 2017

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Mechanism of action of organophosphorus and carbamate insecticides

20 March 2017

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Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

20 March 2017

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Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first 3 years of life among inner-city children

6 April 2017

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Changes in prevalence of parent-reported autism spectrum disorder in school-aged U.S. children: 2007 to 2011-2012.

7 April 2017

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Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study

29 September 2017

1 reference

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Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders

29 September 2017

1 reference

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Drug therapy in autism: a present and future perspective.

29 September 2017

1 reference

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Pharmacologic treatments for the behavioral symptoms associated with autism spectrum disorders across the lifespan

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

A review of executive function deficits and pharmacological management in children and adolescents.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

GABA and Dopamine Release from Different Brain Regions in Mice with Chronic Exposure to Organophosphate Methamidophos.

29 September 2017

1 reference

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AutismKB: an evidence-based knowledgebase of autism genetics.

29 September 2017

1 reference

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The prevalence of autism spectrum disorders in toddlers: a population study of 2-year-old Swedish children

29 September 2017

1 reference

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The role of environmental exposures in neurodegeneration and neurodegenerative diseases

29 September 2017

1 reference

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Alterations in GABAergic biomarkers in the autism brain: research findings and clinical implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Nerve agent intoxication: recent neuropathophysiological findings and subsequent impact on medical management prospects

29 September 2017

1 reference

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Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity.

29 September 2017

1 reference

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Antidepressant use during pregnancy and childhood autism spectrum disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Prenatal PCBs disrupt early neuroendocrine development of the rat hypothalamus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Associating neural alterations and genotype in autism and fragile x syndrome: incorporating perceptual phenotypes in causal modeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Impact of environmental endocrine disrupting chemicals on the development of obesity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Polychlorinated biphenyls and polybrominated diphenyl ethers alter striatal dopamine neurochemistry in synaptosomes from developing rats in an additive manner

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Can autism be triggered by acetaminophen activation of the endocannabinoid system?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Occupational exposure to pesticides increases the risk of incident AD: the Cache County study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

mRNA and protein levels for GABAAalpha4, alpha5, beta1 and GABABR1 receptors are altered in brains from subjects with autism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Fetal and neonatal exposure to three typical environmental chemicals with different mechanisms of action: mixed exposure to phenol, phthalate, and dioxin cancels the effects of sole exposure on mouse midbrain dopaminergic nuclei.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Studies with neuronal cells: From basic studies of mechanisms of neurotoxicity to the prediction of chemical toxicity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Increased serum levels of glutamate in adult patients with autism.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Oestrogen receptor downregulation: an opportunity for extending the window of endocrine therapy in advanced breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Risperidone in children with autism and serious behavioral problems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Linkage and association of the glutamate receptor 6 gene with autism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Medication treatment in subjects with autistic spectrum disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Epilepsy and epileptiform EEG: association with autism and language disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Polychlorinated biphenyls and methylmercury act synergistically to reduce rat brain dopamine content in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Organophosphate and carbamate poisoning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Reactive oxygen species regulated mitochondria-mediated apoptosis in PC12 cells exposed to chlorpyrifos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Aroclor 1254 selectively inhibits expression of glial GLT-1 glutamate transporter in the forebrain of chronically exposed adult rat.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Neurodevelopmental and behavioral toxicity via lactational exposure to the sum of six indicator non-dioxin-like-polychlorinated biphenyls (∑6 NDL-PCBs) in mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Organochlorine insecticides lindane and dieldrin and their binary mixture disturb calcium homeostasis in dopaminergic PC12 cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Protection of dichlorvos induced oxidative stress and nigrostriatal neuronal death by chronic coenzyme Q10 pretreatment

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Brain serotonin and dopamine transporter bindings in adults with high-functioning autism.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Effects of methyl mercury in combination with polychlorinated biphenyls and brominated flame retardants on the uptake of glutamate in rat brain synaptosomes: a mathematical approach for the study of mixtures

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Polychlorinated biphenyl-induced neurotoxicity in organotypic cocultures of developing rat ventral mesencephalon and striatum

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

What's going on? The question of time trends in autism

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

Epidemiology of autism spectrum disorders in adults in the community in England

2 June 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Non-invasive evaluation of the GABAergic/glutamatergic system in autistic patients observed by MEGA-editing proton MR spectroscopy using a clinical 3 tesla instrument.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Role of metabotropic glutamate receptor 7 in autism spectrum disorders: a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Plasma amino acid levels in children with autism and their families

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Serotonin and the autisms: a red flag or a red herring?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

A pilot study of D-cycloserine in subjects with autistic disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Executive function deficits in autism spectrum disorders and attention-deficit/hyperactivity disorder: examining profiles across domains and ages.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Low medial prefrontal dopaminergic activity in autistic children.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Human health risk assessment of endosulfan. I: Toxicology and hazard identification

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

PCB-induced inhibition of the vesicular monoamine transporter predicts reductions in synaptosomal dopamine content

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

The plasticizer di(2-ethylhexyl) phthalate modulates gamma-aminobutyric acid type A and glycine receptor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Effects of in utero and lactational exposure to endosulfan in prefrontal cortex of male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Toxic effects of methoxychlor in rat striatum: modifications in several neurotransmitters

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Repeated exposure of adult rats to Aroclor 1254 induces neuronal injury and impairs the neurochemical manifestations of the NMDA receptor-mediated intracellular signaling in the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. Mechanisms involved

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Differential long-term effects of developmental exposure to polychlorinated biphenyls 52, 138 or 180 on motor activity and neurotransmission. Gender dependence and mechanisms involved.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Alteration of brain neurotransmitters in female rat offspring induced by prenatal administration of 16 and 64 mg/kg of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Toxic effects of methoxychlor administered subcutaneously on the hypothalamic-pituitary-testicular axis in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

In vitro assessment of paraoxon effects on GABA uptake in rat hippocampal synaptosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Synaptosomal GABA uptake decreases in paraoxon-treated rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Long term compulsivity on the 5-choice serial reaction time task after acute Chlorpyrifos exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Different reaction patterns of dopamine content to prenatal exposure to chlorpyrifos in different periods.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Repeated developmental exposure to chlorpyrifos and methyl parathion causes persistent alterations in nicotinic acetylcholine subunit mRNA expression with chlorpyrifos altering dopamine metabolite levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Long-term monoamine changes in the striatum and nucleus accumbens after acute chlorpyrifos exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Prenatal chlorpyrifos exposure elicits presynaptic serotonergic and dopaminergic hyperactivity at adolescence: critical periods for regional and sex-selective effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Effects of monocrotophos pesticide on serotonin metabolism during early development in the sea urchin, Hemicentrotus pulcherrimus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Different effects by sex on hypothalamic-pituitary axis of prepubertal offspring rats produced by in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Impact of gestational and lactational phthalate exposure on hypothalamic content of amino acid neurotransmitters and FSH secretion in peripubertal male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Dicyclohexylphthalate causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Neurochemical effects of chronic dietary and repeated high-level acute exposure to chlorpyrifos in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Polychlorinated biphenyl mixture aroclor 1254-induced oxidative stress plays a role in dopaminergic cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Acute exposure to aroclor 1016 or 1260 differentially affects dopamine transporter and vesicular monoamine transporter 2 levels

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Coplanar PCB congeners increase uterine weight and frontal cortical dopamine in the developing rat: implications for developmental neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Paraoxon inhibits GABA uptake in brain synaptosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Expression of receptors for luteinizing hormone-releasing hormone (LH-RH) in prostate cancers following therapy with LH-RH agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH10083384

Determination of homovanillic acid and vanillylmandelic acid in urine of autistic children by gas chromatography/mass spectrometry.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444

D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774444