Disruption of androgen receptor signaling in males by environmental chemicals (Q28391744)

The Journal of Steroid Biochemistry and Molecular Biology

Europe PubMed Central

title

Disruption of androgen receptor signaling in males by environmental chemicals (English)

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Doug C Luccio-Camelo

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Gail S Prins

series ordinal

2

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language of work or name

English

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publication date

October 2011

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published in

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volume

127

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issue

1-2

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page(s)

74-82

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cites work

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Diastereomers of the brominated flame retardant 1,2-dibromo-4-(1,2 dibromoethyl)cyclohexane induce androgen receptor activation in the hepg2 hepatocellular carcinoma cell line and the lncap prostate cancer cell line

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Perinatal exposure to oestradiol and bisphenol A alters the prostate epigenome and increases susceptibility to carcinogenesis

29 September 2017

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Impact of environmental pollutants on the male: effects on germ cell differentiation

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Testicular dysgenesis syndrome: possible role of endocrine disrupters

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Semen quality in fertile US men in relation to geographical area and pesticide exposure

29 September 2017

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Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro

29 September 2017

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Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells

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Xenoestrogen action in prostate cancer: pleiotropic effects dependent on androgen receptor status.

29 September 2017

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Molecular mechanisms of androgen receptor-mediated gene regulation: structure-function analysis of the AF-1 domain

29 September 2017

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Screening of some anti-androgenic endocrine disruptors using a recombinant cell-based in vitro bioassay

29 September 2017

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Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway.

29 September 2017

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Environmental estrogens: roles in male reproductive tract problems and in breast cancer

29 September 2017

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Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit alpha and beta estrogen activities and antiandrogen activity in reporter cell lines

29 September 2017

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Molecular biology of the androgen receptor

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Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man.

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29 September 2017

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Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat.

29 September 2017

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Effects of antiandrogens on chromatin remodeling and transcription of the integrated mouse mammary tumor virus promoter

29 September 2017

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Cellular and molecular mechanisms of action of linuron: an antiandrogenic herbicide that produces reproductive malformations in male rats

29 September 2017

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Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual di

29 September 2017

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Two distinct isoforms of cDNA encoding rainbow trout androgen receptors

29 September 2017

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Male reproductive health and environmental xenoestrogens

29 September 2017

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29 September 2017

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Reproductive function in rats exposed prenatally to pesticides and polychlorinated biphenyls (PCB)

29 September 2017

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Evaluation of a rapid in vitro androgen receptor transcriptional activation assay using AR-EcoScreen cells

29 September 2017

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Difference in prevalence of congenital cryptorchidism in infants between two Nordic countries.

2 June 2018

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Maternal serum level of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and risk of cryptorchidism, hypospadias, and polythelia among male offspring

2 June 2018

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2 June 2018

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In utero exposure to antiandrogens alters the responsiveness of the prostate to p,p'-DDE in adult rats and may induce prostatic inflammation.

2 June 2018

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Several environmental oestrogens are also anti-androgens

2 June 2018

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2 June 2018

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Germ cell cancer and disorders of spermatogenesis: an environmental connection?

2 June 2018

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2 June 2018

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Endocrine disruptors and reproductive development: a weight-of-evidence overview

2 June 2018

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Cloning and partial sequence of the rabbit androgen receptor: expression in fetal urogenital tissues.

2 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Metabolism and covalent binding of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (o,p,'-DDD). Correlation between adrenocorticolytic activity and metabolic activation by adrenocortical mitochondria

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Molecular cloning of androgen receptors from divergent species with a polymerase chain reaction technique: complete cDNA sequence of the mouse androgen receptor and isolation of androgen receptor cDNA probes from dog, guinea pig and clawed frog

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Reversibility of the inhibitory effect of atrazine and lindane on cytosol 5 alpha-dihydrotestosterone receptor complex formation in rat prostate.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

The effect of chronic ingestion of selected pesticides upon rat ventral prostate homeostasis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Maternal transfer of brominated flame retardants in zebrafish (Danio rerio).

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Structure characterization and thermal stabilities of the isomers of the brominated flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Transgenerational effects of the endocrine disruptor vinclozolin on the prostate transcriptome and adult onset disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Arsenic: extension of its endocrine disruption potential to interference with estrogen receptor-mediated signaling.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Transgenerational effect of the endocrine disruptor vinclozolin on male spermatogenesis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Epigenetic transgenerational actions of endocrine disruptors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Urinary phthalate metabolites and biomarkers of reproductive function in young men.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Prostate-tumor targeting of gene expression by lentiviral vectors containing elements of the probasin promoter

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Short-time exposure to vinclozolin in utero induces testicular maldescent associated with a spinal nucleus alteration of the genitofemoral nerve in rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Phthalate exposure and human semen parameters

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohort

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Electromagnetic fields, polychlorinated biphenyls, and prostate cancer mortality in electric utility workers.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Polychlorinated biphenyls interfere with androgen-induced transcriptional activation and hormone binding

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Spermaturia and serum hormone concentrations at the age of puberty in boys prenatally exposed to polychlorinated biphenyls

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Reproductive toxicity of DDT in adult male rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Prenatal exposure to low doses of bisphenol A alters the periductal stroma and glandular cell function in the rat ventral prostate

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Is there a correlation between organochlorine compounds and undescended testes?

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Sequence and expression of a cDNA encoding the red seabream androgen receptor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Reproductive toxicity and toxicokinetics of lindane in the male offspring of rats exposed during lactation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Investigation of a mechanism for Leydig cell tumorigenesis by linuron in rats.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

The affinity of procymidone to androgen receptor in rats and mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Environmental hormone disruptors: evidence that vinclozolin developmental toxicity is mediated by antiandrogenic metabolites.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Developmental effects of an environmental antiandrogen: the fungicide vinclozolin alters sex differentiation of the male rat.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Changes induced by hexachlorocyclohexane isomers in rat liver and testis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169734

Altered Semen Quality in Relation to Urinary Concentrations of Phthalate Monoester and Oxidative Metabolites

27 November 2018

1 reference

12 December 2020

Effects of Neonatally-Administered DDT Homologs on Reproductive Function in Male and Female Rats

1 reference

12 December 2020

Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat

1 reference

12 December 2020

Demographic and seasonal influences on human serum pesticide residue levels

1 reference

12 December 2020

Farming and prostate cancer mortality

1 reference

12 December 2020

Three-dimensional quantitative structure--activity relationships for androgen receptor ligands

1 reference

12 December 2020

Effect of methoxychlor on reproductive systems of the rat

1 reference

12 December 2020

High organochlorine body burden in women with estrogen receptor-positive breast cancer

1 reference

12 December 2020

10.1016/J.JSBMB.2011.04.004

Identifiers

DOI

1 reference

5007353

5007353

1 reference

1 reference

1 reference