Chronic matrix metalloproteinase inhibition retards age-associated arterial proinflammation and increase in blood pressure (Q28392730)

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Jing Zhang

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Richard Telljohann

3

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Liqun Jiang

4

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James Wu

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Robert E Monticone

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Kapil Kapoor

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Mark Talan

Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries

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language of work or name

English

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publication date

August 2012

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published in

Hypertension

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volume

60

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issue

2

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page(s)

459-66

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cites work

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Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.

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A Dominant Negative Inhibitor Indicates that Monocyte Chemoattractant Protein 1 Functions as a Dimer

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Initial characterization of a neutral metalloproteinase, active on native 3/4-collagen fragments, synthesized by ROS 17/2.8 osteoblastic cells, periodontal fibroblasts, and identified in gingival crevicular fluid

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27 November 2018

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Combination of Tumor Necrosis Factor-α Ablation and Matrix Metalloproteinase Inhibition Prevents Heart Failure After Pressure Overload in Tissue Inhibitor of Metalloproteinase-3 Knock-Out Mice

27 November 2018

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27 November 2018

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Altered regulation of matrix metalloproteinase-2 in aortic remodeling during aging.

27 November 2018

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Coronary and aortic vasoreactivity protection with endothelin receptor antagonist, bosentan, after ischemia and hypoxia in aged rats

27 November 2018

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Identification of protease(s) capable of further degrading native 3/4- and 1/4-collagen fragments generated by collagenase from native type I collagen in human neutrophils

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12 December 2020

Coronary artery calcification is related to functional polymorphism of matrix metalloproteinase 3: the Helsinki Sudden Death Study

1 reference

12 December 2020

Aerobic exercise training reduces plasma endothelin-1 concentration in older women

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12 December 2020

Effects of matrix metalloproteinase inhibition on ventricular remodeling due to volume overload

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12 December 2020

Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells

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12 December 2020

Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive rats

1 reference

12 December 2020

Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failure

1 reference

12 December 2020

Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor

1 reference

12 December 2020

Proinflammatory Profile Within the Grossly Normal Aged Human Aortic Wall

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12 December 2020

Effect of chronic ANG I-converting enzyme inhibition on aging processes. II. Large arteries

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12 December 2020

Myocardial Infarct Expansion and Matrix Metalloproteinase Inhibition

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12 December 2020

Matrix Metalloproteinase-3 Genotype Contributes to Age-Related Aortic Stiffening Through Modulation of Gene and Protein Expression

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12 December 2020

Matrix Metalloproteinase 2 Activation of Transforming Growth Factor-β1 (TGF-β1) and TGF-β1–Type II Receptor Signaling Within the Aged Arterial Wall

1 reference

12 December 2020

Endothelin-1 vasoconstriction and the age-related decline in endothelium-dependent vasodilatation in men

1 reference

12 December 2020

Long-term mineralocorticoid receptor blockade reduces fibrosis and improves cardiac performance and coronary hemodynamics in elderly SHR

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12 December 2020

10.1161/HYPERTENSIONAHA.112.191270

Identifiers

DOI

1 reference

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PubMed publication ID

22689745

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