Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription (Q28395088)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27211851%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Hozumi Motohashi

9

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6 June 2020

author name string

Eri H Kobayashi

1

1 reference

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6 June 2020

Ryo Funayama

3

1 reference

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6 June 2020

Takeshi Nagashima

4

1 reference

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6 June 2020

Makiko Hayashi

5

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6 June 2020

Hiroki Sekine

6

1 reference

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6 June 2020

Nobuyuki Tanaka

7

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6 June 2020

Takashi Moriguchi

8

1 reference

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6 June 2020

Keiko Nakayama

10

1 reference

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6 June 2020

Masayuki Yamamoto

11

1 reference

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6 June 2020

language of work or name

English

0 references

publication date

23 May 2016

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published in

Nature Communications

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volume

7

1 reference

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6 June 2020

page(s)

11624

1 reference

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Creative Commons Attribution 4.0 International

6 June 2020

copyright license

start time

23 May 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Roles nrf2 plays in myeloid cells and related disorders

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19 March 2017

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Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis

19 March 2017

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The Sequence Alignment/Map format and SAMtools

19 March 2017

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Fast and accurate short read alignment with Burrows-Wheeler transform

19 March 2017

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19 March 2017

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Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2

19 March 2017

1 reference

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Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

19 March 2017

1 reference

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

19 March 2017

1 reference

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

19 March 2017

1 reference

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Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)

19 March 2017

1 reference

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Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

19 March 2017

1 reference

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The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

19 March 2017

1 reference

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BEDTools: a flexible suite of utilities for comparing genomic features

19 March 2017

1 reference

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Interleukin-1-receptor antagonist in type 2 diabetes mellitus

7 April 2017

1 reference

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The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression

7 April 2017

1 reference

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Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice

29 September 2017

1 reference

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BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia

29 September 2017

1 reference

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Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.

29 September 2017

1 reference

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Post-transcriptional regulation of gene expression in innate immunity.

29 September 2017

1 reference

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Targeting inflammation in the treatment of type 2 diabetes: time to start

29 September 2017

1 reference

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Dimethyl fumarate: a review of its use in patients with relapsing-remitting multiple sclerosis

29 September 2017

1 reference

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MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation.

29 September 2017

1 reference

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Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms

29 September 2017

1 reference

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The Keap1-Nrf2 system prevents onset of diabetes mellitus

29 September 2017

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Toward clinical application of the Keap1-Nrf2 pathway

29 September 2017

1 reference

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Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels.

29 September 2017

1 reference

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Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes

29 September 2017

1 reference

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Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks

29 September 2017

1 reference

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Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

29 September 2017

1 reference

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Transcriptional regulation of macrophage polarization: enabling diversity with identity

29 September 2017

1 reference

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Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Genetic analysis of cytoprotective functions supported by graded expression of Keap1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Nrf2-deficient female mice develop lupus-like autoimmune nephritis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879264

Myeloid-derived suppressor cells attenuate TH1 development through IL-6 production to promote tumor progression

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27211851

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS11624

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27211851%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 June 2020

ADS bibcode

2016NatCo...711624K

0 references

1010316551

0 references

Fatcat ID

release_jdpqg5g2lfgdpfhrqajno3rmgu

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27211851%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

2 references