Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance (Q28476322)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876375%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876375%20AND%20SRC:MED&resulttype=core&format=json

antifungal drug resistance

11 February 2020

main subject

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876375%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Anna Selmecki

1

1 reference

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11 February 2020

Leah E Cowen

3

1 reference

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11 February 2020

author name string

Keely Dulmage

2

1 reference

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11 February 2020

James B Anderson

4

1 reference

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11 February 2020

language of work or name

English

0 references

publication date

30 October 2009

1 reference

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11 February 2020

1 reference

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11 February 2020

volume

5

1 reference

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11 February 2020

issue

10

1 reference

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11 February 2020

page(s)

e1000705

1 reference

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Creative Commons Attribution 4.0 International

11 February 2020

copyright license

start time

30 October 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains

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Effects of aneuploidy on cellular physiology and cell division in haploid yeast

29 September 2017

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29 September 2017

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A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

29 September 2017

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Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi

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Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans

29 September 2017

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TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

29 September 2017

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29 September 2017

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Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains

29 September 2017

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Multistep carcinogenesis: a chain reaction of aneuploidizations

29 September 2017

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29 September 2017

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29 September 2017

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Calcineurin is essential for survival during membrane stress in Candida albicans

29 September 2017

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Origin of multidrug resistance in cells with and without multidrug resistance genes: chromosome reassortments catalyzed by aneuploidy

29 September 2017

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Divergence in fitness and evolution of drug resistance in experimental populations of Candida albicans

29 September 2017

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Explaining the high mutation rates of cancer cells to drug and multidrug resistance by chromosome reassortments that are catalyzed by aneuploidy

29 September 2017

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29 September 2017

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Overexpression of Erg11p by the regulatable GAL1 promoter confers fluconazole resistance in Saccharomyces cerevisiae.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Aneuploid chromosomes are highly unstable during DNA transformation of Candida albicans

29 September 2017

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Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor

2 June 2018

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2 June 2018

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Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes

2 June 2018

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Comparative genome hybridization reveals widespread aneuploidy in Candida albicans laboratory strains.

2 June 2018

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2 June 2018

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Candidemia in allogeneic blood and marrow transplant recipients: evolution of risk factors after the adoption of prophylactic fluconazole.

2 June 2018

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Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans

21 January 2018

1 reference

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An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1.

21 January 2018

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Rates of DNA sequence evolution in experimental populations of Escherichia coli during 20,000 generations

21 January 2018

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Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence

21 January 2018

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Genotoxicity testing of fluconazole in vivo and in vitro.

21 January 2018

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Widespread aneuploidy revealed by DNA microarray expression profiling.

21 January 2018

1 reference

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Homozygosity at the Candida albicans MTL locus associated with azole resistance

21 January 2018

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Multiple duplications of yeast hexose transport genes in response to selection in a glucose-limited environment

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19876375

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1000705

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876375%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876375%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

19876375

2 references