Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip (Q28476458)

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11 February 2020

title

Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip (English)

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11 February 2020

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5

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11 February 2020

Yves Grandvalet

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11 February 2020

Cécile Legallais

7

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author name string

Jean Matthieu Prot

1

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11 February 2020

Anne-Sophie Briffaut

2

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11 February 2020

Franck Letourneur

3

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11 February 2020

Philippe Chafey

4

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11 February 2020

Eric Leclerc

8

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11 February 2020

language of work or name

English

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publication date

8 August 2011

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11 February 2020

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11 February 2020

volume

6

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11 February 2020

issue

8

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11 February 2020

page(s)

e21268

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Creative Commons Attribution 4.0 International

11 February 2020

copyright license

start time

8 August 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Intracellular signaling mechanisms of acetaminophen-induced liver cell death

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Cell culture model for acetaminophen-induced hepatocyte death in vivo

29 September 2017

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Calcium Dependence of Toxic Cell Death: A Final Common Pathway

29 September 2017

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Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human

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Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice

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Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo

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Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters.

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Toxicogenomic analysis of N-nitrosomorpholine induced changes in rat liver: comparison of genomic and proteomic responses and anchoring to histopathological parameters

2 June 2018

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Interspecies differences in acetaminophen sensitivity of human, rat, and mouse primary hepatocytes

21 January 2018

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Relative binding of therapeutic drugs by sera of seven mammalian species

21 January 2018

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Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

21 January 2018

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Perfused microreactors for liver tissue engineering

21 January 2018

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Implication of alterations in intracellular calcium ion homoeostasis in the advent of paracetamol-induced cytotoxicity in primary mouse hepatocyte monolayer cultures

27 November 2018

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12 December 2020

Ultrastructural effects of acetaminophen in isolated mouse hepatocytes

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12 December 2020

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism

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12 December 2020

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice

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12 December 2020

Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans

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12 December 2020

Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3'-hydroxyacetanilide, in mouse liver

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12 December 2020

Modulation of serum growth factor signal transduction in Hepa 1-6 cells by acetaminophen: an inhibition of c-myc expression, NF-kappaB activation, and Raf-1 kinase activity

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12 December 2020

Ca2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen

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12 December 2020

10.1371/JOURNAL.PONE.0021268

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21857903%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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11 February 2020

PubMed publication ID

21857903

1 reference