Rationally designed interfacial peptides are efficient in vitro inhibitors of HIV-1 capsid assembly with antiviral activity (Q28476840)

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13 February 2020

title

Rationally designed interfacial peptides are efficient in vitro inhibitors of HIV-1 capsid assembly with antiviral activity (English)

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13 February 2020

5

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13 February 2020

Claudio N. Cavasotto

7

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13 February 2020

Adrian Velazquez-campoy

8

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13 February 2020

Miguel A Martinez

10

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13 February 2020

author name string

Rebeca Bocanegra

1

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13 February 2020

María Nevot

2

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13 February 2020

Rosa Doménech

3

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13 February 2020

Inmaculada López

4

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13 February 2020

Alicia Rodríguez-Huete

6

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13 February 2020

Javier Gómez

9

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13 February 2020

José Luis Neira

11

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13 February 2020

Mauricio G Mateu

12

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13 February 2020

language of work or name

English

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publication date

8 September 2011

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13 February 2020

1 reference

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13 February 2020

volume

6

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13 February 2020

issue

9

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13 February 2020

page(s)

e23877

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Creative Commons Attribution 4.0 International

13 February 2020

copyright license

start time

8 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function

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X-ray structures of the hexameric building block of the HIV capsid

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Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein

19 March 2017

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Solution Structure of a Hydrocarbon Stapled Peptide Inhibitor in Complex with Monomeric C-terminal Domain of HIV-1 Capsid

19 March 2017

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Solution structure of a double mutant of the carboxy-terminal dimerization domain of the HIV-1 capsid protein

19 March 2017

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Structure of full-length HIV-1 CA: a model for the mature capsid lattice

19 March 2017

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Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

19 March 2017

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Flexibility in HIV-1 Assembly Subunits: Solution Structure of the Monomeric C-Terminal Domain of the Capsid Protein

19 March 2017

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Domain-swapped dimerization of the HIV-1 capsid C-terminal domain

19 March 2017

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Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution

19 March 2017

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Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein

19 March 2017

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Calculation of protein extinction coefficients from amino acid sequence data

19 March 2017

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Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

19 March 2017

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Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway

19 March 2017

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19 March 2017

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RASMOL: biomolecular graphics for all

19 March 2017

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Anatomy of hot spots in protein interfaces

7 April 2017

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High-density miniaturized thermal shift assays as a general strategy for drug discovery

7 April 2017

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Second-site compensatory mutations of HIV-1 capsid mutations

7 April 2017

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Effects of macromolecular crowding on the inhibition of virus assembly and virus-cell receptor recognition.

29 September 2017

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Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization

29 September 2017

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Identifying the amylome, proteins capable of forming amyloid-like fibrils

29 September 2017

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The capsid protein of human immunodeficiency virus: interactions of HIV-1 capsid with host protein factors

29 September 2017

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The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly

29 September 2017

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The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly

29 September 2017

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Characterization of the in vitro HIV-1 capsid assembly pathway

29 September 2017

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Capsid (CA) protein as a novel drug target: recent progress in the research of HIV-1 CA inhibitors

29 September 2017

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Peptide inhibitors of hepatitis C virus core oligomerization and virus production

29 September 2017

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HIV-1 capsid assembly inhibitor (CAI) peptide: structural preferences and delivery into human embryonic lung cells and lymphocytes

29 September 2017

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The structural biology of HIV assembly

29 September 2017

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A cell-penetrating helical peptide as a potential HIV-1 inhibitor

29 September 2017

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Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later

29 September 2017

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Effect of macromolecular crowding agents on human immunodeficiency virus type 1 capsid protein assembly in vitro.

29 September 2017

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A peptide inhibitor of HIV-1 assembly in vitro

29 September 2017

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Glycine-amide is an active metabolite of the antiretroviral tripeptide glycyl-prolyl-glycine-amide

29 September 2017

1 reference

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Small compounds targeted to subunit interfaces arrest maturation in a nonenveloped, icosahedral animal virus

29 September 2017

1 reference

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The molecular basis of HIV capsid assembly--five years of progress

29 September 2017

1 reference

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Assembly properties of the human immunodeficiency virus type 1 CA protein

29 September 2017

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Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein

29 September 2017

1 reference

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Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids

29 September 2017

1 reference

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Tripeptide interference with human immunodeficiency virus type 1 morphogenesis

29 September 2017

1 reference

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Kinetic analysis of the role of intersubunit interactions in human immunodeficiency virus type 1 capsid protein assembly in vitro

29 September 2017

1 reference

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In vitro assembly properties of purified bacterially expressed capsid proteins of human immunodeficiency virus

29 September 2017

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Isotope-edited multidimensional NMR of calcineurin B in the presence of the non-deuterated detergent CHAPS.

29 September 2017

1 reference

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Assembly of recombinant human immunodeficiency virus type 1 capsid protein in vitro

29 September 2017

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Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry.

29 September 2017

1 reference

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Image reconstructions of helical assemblies of the HIV-1 CA protein

2 June 2018

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Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques.

2 June 2018

1 reference

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Blocking HIV-1 virus assembly

2 June 2018

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Biophysical and structural studies on the capsid protein of the human immunodeficiency virus type 1: a new drug target?

21 January 2018

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Antiviral inhibition of the HIV-1 capsid protein

21 January 2018

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The HIV-1 capsid protein C-terminal domain in complex with a virus assembly inhibitor

21 January 2018

1 reference

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Activity of the small modified amino acid alpha-hydroxy glycineamide on in vitro and in vivo human immunodeficiency virus type 1 capsid assembly and infectivity.

21 January 2018

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Dendrimers as potential inhibitors of the dimerization of the capsid protein of HIV-1.

21 January 2018

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Thermodynamic dissection of a low affinity protein-protein interface involved in human immunodeficiency virus assembly

21 January 2018

1 reference

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The dimerization domain of the HIV-1 capsid protein binds a capsid protein-derived peptide: a biophysical characterization

21 January 2018

1 reference

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Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

21 January 2018

1 reference

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Conformational stability of dimeric and monomeric forms of the C-terminal domain of human immunodeficiency virus-1 capsid protein

21 January 2018

1 reference

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Electrostatic repulsion, compensatory mutations, and long-range non-additive effects at the dimerization interface of the HIV capsid protein

21 January 2018

1 reference

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2,4-Diaryl-4,6,7,8-tetrahydroquinazolin-5(1H)-one derivatives as anti-HBV agents targeting at capsid assembly

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21931621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Stabilization of Proteins by Ligand Binding: Application to Drug Screening and Determination of Unfolding Energetics

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21931621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The isolated C-terminal domain of Ring1B is a dimer made of stable, well-structured monomers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21931621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0023877

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931621%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21931621%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

21931621

1 reference