Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast (Q28478363)

6

0 references

Guri Giaever

7

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Corey Nislow

8

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Iwona Migdal

Iwona Migdal

4

0 references

Robert Wysocki

Robert Wysocki

10

0 references

Morten Grøtli

Morten Grøtli

12

0 references

Stefan Hohmann

Stefan Hohmann

9

0 references

author name string

Peter Dinér

1

0 references

Jenny Veide Vilg

2

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Jimmy Kjellén

3

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Terese Andersson

5

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Markus J Tamás

The genetic landscape of a cell

11

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language of work or name

English

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publication date

2011

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published in

PLOS One

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volume

6

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issue

5

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page(s)

e20012

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cites work

1 reference

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Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast

19 March 2017

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The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast.

19 March 2017

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Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity

19 March 2017

1 reference

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Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1.

19 March 2017

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Global mapping of the yeast genetic interaction network

19 March 2017

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Targeting the MEF2-like transcription factor Smp1 by the stress-activated Hog1 mitogen-activated protein kinase

19 March 2017

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

19 March 2017

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Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase Hog1.

19 March 2017

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The transcriptional response of Saccharomyces cerevisiae to osmotic shock. Hot1p and Msn2p/Msn4p are required for the induction of subsets of high osmolarity glycerol pathway-dependent genes.

19 March 2017

1 reference

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The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae

19 March 2017

1 reference

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Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases

19 March 2017

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A two-component system that regulates an osmosensing MAP kinase cascade in yeast

19 March 2017

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p38 MAP-kinases pathway regulation, function and role in human diseases

19 March 2017

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

7 April 2017

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Osmotic stress signaling and osmoadaptation in yeasts

7 April 2017

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

7 April 2017

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Multilayered control of gene expression by stress-activated protein kinases.

7 April 2017

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Control of high osmolarity signalling in the yeast Saccharomyces cerevisiae

29 September 2017

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Stress resistance and signal fidelity independent of nuclear MAPK function

29 September 2017

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High-throughput kinase profiling as a platform for drug discovery

29 September 2017

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Cyclin B1 proteolysis via p38 MAPK signaling participates in G2 checkpoint elicited by arsenite

29 September 2017

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A rapid method for determining protein kinase phosphorylation specificity

29 September 2017

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MAP kinase-mediated stress relief that precedes and regulates the timing of transcriptional induction

29 September 2017

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Protein kinase inhibitors: insights into drug design from structure.

29 September 2017

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The emerging power of chemical genetics

29 September 2017

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Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiae

29 September 2017

1 reference

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The stress-activated protein kinase Hog1 mediates S phase delay in response to osmostress

29 September 2017

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Mitogen-activated protein kinase Hog1 mediates adaptation to G1 checkpoint arrest during arsenite and hyperosmotic stress

2 June 2018

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Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele

2 June 2018

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Involvement of p38 mitogen-activated protein kinase in the cell growth inhibition by sodium arsenite

2 June 2018

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Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

2 June 2018

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Chemical genetics: where genetics and pharmacology meet

2 June 2018

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Dissecting yeast Hog1 MAP kinase pathway using a chemical genetic approach.

21 January 2018

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Dynamic signaling in the Hog1 MAPK pathway relies on high basal signal transduction.

21 January 2018

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Selective p38alpha inhibitors clinically evaluated for the treatment of chronic inflammatory disorders

21 January 2018

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Simple, Efficient Catalyst System for the Palladium-Catalyzed Amination of Aryl Chlorides, Bromides, and Triflates

21 January 2018

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Robustness and fragility in the yeast high osmolarity glycerol (HOG) signal-transduction pathway

21 January 2018

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Automated screening in environmental arrays allows analysis of quantitative phenotypic profiles in Saccharomyces cerevisiae.

21 January 2018

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Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures.

21 January 2018

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PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1.

21 January 2018

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Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models

27 November 2018

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