Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors (Q28481220)

2

Riccardo

Montioli

1 reference

20 October 2023

Alessandro Paiardini

3

Alessandro

Paiardini

1 reference

20 October 2023

Barbara Cellini

4

Barbara

Cellini

1 reference

20 October 2023

Francesco Bossa

7

Francesco

Bossa

1 reference

20 October 2023

Carla Borri Voltattorni

8

Carla

Creative Commons Attribution 4.0 International

Borri Voltattorni

1 reference

20 October 2023

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS One

0 references

volume

7

0 references

issue

2

0 references

page(s)

e31610

0 references

copyright license

start time

23 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Virtual screening strategies in drug discovery

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Virtual Computational Chemistry Laboratory – Design and Description

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

ZINC--a free database of commercially available compounds for virtual screening

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Medical treatment of Parkinson's disease: today and the future

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Pharmacophore-based virtual screening versus docking-based virtual screening: a benchmark comparison against eight targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Levodopa: past, present, and future

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

How does consensus scoring work for virtual library screening? An idealized computer experiment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Detailed analysis of scoring functions for virtual screening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Drug-like properties and the causes of poor solubility and poor permeability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

L-dihydroxyphenylalanine and its decarboxylase: new ideas on their neuroregulatory roles.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Interaction of N-(DL-seryl)N′-(2,3,4-trihydroxybenzyl)-hydrazine with L-Dopa decarboxylase from pig kidney

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

An investigation of the assay of dopamine using trinitrobenzensulphonic acid

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

DOVIS 2.0: an efficient and easy to use parallel virtual screening tool based on AutoDock 4.0.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Reaction specificity of native and nicked 3,4-dihydroxyphenylalanine decarboxylase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Mechanism-based inactivation of dopa decarboxylase by serotonin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

The inverse relationship between the activity of pyridoxal kinase and the level of biogenic amines in rabbit brain

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Interaction of L-alpha-methyl-alpha-hydrazino-3,4 dihydroxyphenylpropionic acid with dopa-decarboxylase from pig kidney

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

Mutation of residues in the coenzyme binding pocket of Dopa decarboxylase. Effects on catalytic properties

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031610

Mutation of cysteine 111 in Dopa decarboxylase leads to active site perturbation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031610

Dissociation, unfolding and refolding trials of pig kidney 3,4-dihydroxyphenylalanine (dopa) decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031610

Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031610

Protein-based virtual screening of chemical databases. 1. Evaluation of different docking/scoring combinations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031610

Mutation of tyrosine 332 to phenylalanine converts dopa decarboxylase into a decarboxylation-dependent oxidative deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031610

An analysis of the binding efficiencies of drugs and their leads in successful drug discovery programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031610

Using AutoDock for ligand-receptor docking

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285636

The interaction of 2,3,4-trihydroxybenzylhydrazine with DOPA decarboxylase from pig kidney

27 November 2018

1 reference

12 December 2020

1 reference

12 December 2020

Effects of benserazide, carbidopa and isoniazid administration on tryptophan-nicotinamide nucleotide metabolism in the rat

1 reference

12 December 2020

An essential arginine residue at the binding site of pig kidney 3,4-dihydroxyphenylalanine decarboxylase

1 reference

12 December 2020

Molecular insights into the pathogenicity of variants associated with the aromatic amino acid decarboxylase deficiency

1 reference

12 December 2020

Elevated plasma levels of homocysteine in Parkinson's disease

1 reference

12 December 2020

Pyridoxal phosphokinases. II. Effects of inhibitors

1 reference

12 December 2020

Sulfate and cysteine levels in the plasma of patients with Parkinson's disease

1 reference

12 December 2020

Aromatic amino acid methyl ester analogs form quinonoidal species with Dopa decarboxylase

1 reference

12 December 2020

A spectrophotometric assay for Drosophila dopa decarboxylase

1 reference

12 December 2020

Inhibition in vitro of the enzymes of the oxidative pathway of tryptophan metabolism and of nicotinamide nucleotide synthesis by benserazide, carbidopa and isoniazid

1 reference

12 December 2020

Competitive inhibition of 3, 4-dihydroxyphenylalanine (DOPA) decarboxylase in vitro

1 reference

12 December 2020

Spectral properties of the coenzyme bound to DOPA decarboxylase from pig kidney

1 reference

12 December 2020

Pharmacokinetic and metabolic studies of the decarboxylase inhibitor benserazide in animals and man

1 reference

12 December 2020

Interaction of aromatic amino acids in D and L forms with 3,4-dihydroxyphenylalanine decarboxylase from pig kidney

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0031610

Identifiers

DOI

1 reference

889088

ADS bibcode

2012PLoSO...731610D

0 references

889088

1 reference

1 reference

1 reference