Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS (Q28481340)

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English	Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS	scientific article

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Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS (English)

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amyotrophic lateral sclerosis

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Axel Petzold

2

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author name string

Ching-Hua Lu

1

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Bernadett Kalmar

3

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James Dick

4

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Andrea Malaspina

5

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Linda Greensmith

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publication date

2012

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7

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7

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e40998

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Creative Commons Attribution 4.0 International

16 July 2012

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April 2022 Public Data File from Crossref

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Late stage treatment with arimoclomol delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS

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Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

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19 March 2017

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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7 April 2017

Roadmap and standard operating procedures for biobanking and discovery of neurochemical markers in ALS.

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29 September 2017

Amyotrophic lateral sclerosis: a neurovascular disease.

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29 September 2017

Combination of neurofilament heavy chain and complement C3 as CSF biomarkers for ALS.

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29 September 2017

The application of biomarkers in clinical trials for motor neuron disease

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29 September 2017

Toward more efficient clinical trials for amyotrophic lateral sclerosis

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29 September 2017

Arimoclomol: a potential therapy under development for ALS.

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29 September 2017

Prognostic factors in ALS: A critical review

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29 September 2017

Immunoreactivity of the phosphorylated axonal neurofilament H subunit (pNF-H) in blood of ALS model rodents and ALS patients: evaluation of blood pNF-H as a potential ALS biomarker

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29 September 2017

Awaji diagnostic algorithm increases sensitivity of El Escorial criteria for ALS diagnosis

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29 September 2017

Biochemical markers in CSF of ALS patients

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29 September 2017

Review of the multiple aspects of neurofilament functions, and their possible contribution to neurodegeneration

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29 September 2017

Levels of brain related proteins in cerebrospinal fluid: an aid in the differential diagnosis of parkinsonian disorders

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29 September 2017

Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis

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29 September 2017

Behavioral phenotyping strategies for mutant mice

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29 September 2017

CSF neurofilament proteins in the differential diagnosis of dementia

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29 September 2017

Updating motor unit number estimation (MUNE).

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29 September 2017

The pathobiology of amyotrophic lateral sclerosis: a proteinopathy?

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29 September 2017

Neurofilament phosphoforms: surrogate markers for axonal injury, degeneration and loss

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29 September 2017

Assessment of disease progression in motor neuron disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397981

29 September 2017

SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice.

1 reference

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29 September 2017

Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397981

29 September 2017

Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397981

29 September 2017

Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis

2 references

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29 September 2017

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

Evidence for acute neurotoxicity after chemotherapy

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2 June 2018

Elevated neurofilament levels in neurological diseases.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397981

2 June 2018

Riluzole therapy for motor neurone disease: an early Australian experience (1996-2002).

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

Axonal damage markers in cerebrospinal fluid are increased in ALS.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

Patients with Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases Have Increased Levels of Neurofilament Protein in CSF

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

A method to solubilise protein aggregates for immunoassay quantification which overcomes the neurofilament "hook" effect.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

The effect of peripheral nerve injury on disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

A specific ELISA for measuring neurofilament heavy chain phosphoforms

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

Treatment with a coinducer of the heat shock response delays muscle denervation in the SOD1-G93A mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040998

21 January 2018

Neurofilament a biomarker of neurodegeneration in autoimmune encephalomyelitis

1 reference

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27 November 2018

CSF neurofilament proteins levels are elevated in sporadic Creutzfeldt-Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397981

27 November 2018

Neurofilament light as a prognostic marker in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The localization of the motoneurons supplying the hindlimb muscles of the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation protects neurofilaments against proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid neurofilament light levels in amyotrophic lateral sclerosis: impact of SOD1 genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/22815892

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0040998

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Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

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