SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids (Q28481634)

2

0 references

Lingyun Li

3

0 references

Trisha Fremgen

4

0 references

Erin Murphy

5

0 references

Angela Quinn

6

0 references

Stephen L Madden

7

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Hans-Peter Biemann

8

0 references

Bing Wang

9

0 references

Aharon Cohen

10

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Svetlana Komarnitsky

11

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Kate Jancsics

12

0 references

Brad Hirth

13

0 references

Christopher G F Cooper

14

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Edward Lee

15

0 references

Sean Wilson

16

0 references

Roy Krumbholz

17

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Steven Schmid

18

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Yibin Xiang

19

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Michael Booker

20

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James Lillie

21

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Kara Carter

Creative Commons Attribution 4.0 International

22

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language of work or name

English

0 references

publication date

2012

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published in

PLOS One

0 references

volume

7

0 references

issue

3

0 references

page(s)

e33823

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copyright license

start time

22 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling

1 reference

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Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates

19 March 2017

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Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals

19 March 2017

1 reference

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Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells

19 March 2017

1 reference

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Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors

29 September 2017

1 reference

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Targeting fatty acid synthase in breast and endometrial cancer: An alternative to selective estrogen receptor modulators?

29 September 2017

1 reference

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Fatty acid synthase and cancer: new application of an old pathway

29 September 2017

1 reference

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Fatty acid synthase-catalyzed de novo fatty acid biosynthesis: from anabolic-energy-storage pathway in normal tissues to jack-of-all-trades in cancer cells.

29 September 2017

1 reference

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Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310881

Synthesis and antitumor activity of an inhibitor of fatty acid synthase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310881

Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310881

Membrane lipid perturbation modifies the set point of the temperature of heat shock response in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310881

The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310881

Mechanism responsible for 5-(tetradecyloxy)-2-furoic acid inhibition of hepatic lipogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310881

Fatty acid synthase expression in endometrial carcinoma: correlation with cell proliferation and hormone receptors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310881

Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033823

Discovery of 1-(4-phenoxypiperidin-1-yl)-2-arylaminoethanone stearoyl-CoA desaturase 1 inhibitors.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033823

Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033823

Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22457791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

3-Aryl-4-hydroxyquinolin-2(1H)-one derivatives as type I fatty acid synthase inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22457791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0033823

1 reference

1107313

ADS bibcode

2012PLoSO...733823M

0 references

1107313

1 reference

1 reference

1 reference