Internalization and down-regulation of the ALK receptor in neuroblastoma cell lines upon monoclonal antibodies treatment (Q28482066)

12

Isabelle Janoueix-Lerosey

0 references

Olivier Delattre

Olivier Delattre

11

0 references

Pierre Mazot

1

Pierre Mazot

0 references

Alex Cazes

2

Alex Cazes

0 references

Florent Dingli

3

Florent Dingli

0 references

Bérangère Lombard

7

Bérangère Lombard

0 references

Loew Damarys

8

Damarys Loew

0 references

author name string

Joffrey Degoutin

4

0 references

Théano Irinopoulou

5

0 references

Marie-Claude Boutterin

6

0 references

Bengt Hallberg

9

0 references

Ruth Helen Palmer

10

0 references

Marc Vigny

Creative Commons Attribution 4.0 International

13

0 references

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS One

0 references

volume

7

0 references

issue

3

0 references

page(s)

e33581

0 references

copyright license

start time

30 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

19 March 2017

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The constitutive activity of the ALK mutated at positions F1174 or R1275 impairs receptor trafficking

19 March 2017

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Ubiquitin conjugase UBCH8 targets active FMS-like tyrosine kinase 3 for proteasomal degradation

29 September 2017

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29 September 2017

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C. elegans anaplastic lymphoma kinase ortholog SCD-2 controls dauer formation by modulating TGF-beta signaling

29 September 2017

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EGF receptor ubiquitination is not necessary for its internalization

29 September 2017

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In contrast to agonist monoclonal antibodies, both C-terminal truncated form and full length form of Pleiotrophin failed to activate vertebrate ALK (anaplastic lymphoma kinase)?

29 September 2017

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Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.

29 September 2017

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Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation

29 September 2017

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Activation and inhibition of anaplastic lymphoma kinase receptor tyrosine kinase by monoclonal antibodies and absence of agonist activity of pleiotrophin.

29 September 2017

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Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases

29 September 2017

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Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.

29 September 2017

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ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth

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Cells release prions in association with exosomes

29 September 2017

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A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster

29 September 2017

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A ligand-inducible anaplastic lymphoma kinase chimera is endocytosis impaired

29 September 2017

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A ligand-inducible epidermal growth factor receptor/anaplastic lymphoma kinase chimera promotes mitogenesis and transforming properties in 3T3 cells

2 June 2018

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Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking

21 January 2018

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A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner

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High incidence of DNA mutations and gene amplifications of theALKgene in advanced sporadic neuroblastoma tumours

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https://pubmed.ncbi.nlm.nih.gov/22479414