Norcantharidin facilitates LPS-mediated immune responses by up-regulation of AKT/NF-κB signaling in macrophages (Q28483653)

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13 February 2020

title

Norcantharidin facilitates LPS-mediated immune responses by up-regulation of AKT/NF-κB signaling in macrophages (English)

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13 February 2020

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6

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13 February 2020

Bing Du

8

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13 February 2020

author name string

Qufei Zhao

1

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13 February 2020

Yu Qian

2

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13 February 2020

Ruimei Li

3

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13 February 2020

Binghe Tan

4

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13 February 2020

Honghui Han

5

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13 February 2020

Min Qian

7

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language of work or name

English

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publication date

11 September 2012

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13 February 2020

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13 February 2020

volume

7

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issue

9

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13 February 2020

page(s)

e44956

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Creative Commons Attribution 4.0 International

13 February 2020

copyright license

start time

11 September 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding [...]

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Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

19 March 2017

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19 March 2017

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Paradoxical roles of the immune system during cancer development

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Innate immunity: the virtues of a nonclonal system of recognition

7 April 2017

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Recognition of microorganisms and activation of the immune response

7 April 2017

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7 April 2017

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Inhibitory effects of norcantharidin against human lung cancer cell growth and migration

7 April 2017

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Norcantharidin is a small-molecule synthetic compound with anti-angiogenesis effect

29 September 2017

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A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells

29 September 2017

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The value of drug repositioning in the current pharmaceutical market

29 September 2017

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Structures of the toll-like receptor family and its ligand complexes

29 September 2017

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Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

29 September 2017

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The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IkappaB kinase complex

29 September 2017

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Norcantharidin-induced apoptosis in oral cancer cells is associated with an increase of proapoptotic to antiapoptotic protein ratio.

29 September 2017

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Toll-like receptors induce a phagocytic gene program through p38.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

29 September 2017

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Innate immunity: impact on the adaptive immune response

2 June 2018

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2 June 2018

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The anti-proliferative effects of norcantharidin on human HepG2 cells in cell culture

27 November 2018

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27 November 2018

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27 November 2018

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12 December 2020

Scavenger receptors in innate immunity

1 reference

12 December 2020

Effects of matrix proteins on the expression of matrix metalloproteinase-2, -9, and -14 and tissue inhibitors of metalloproteinases in human cytotrophoblast cells during the first trimester

1 reference

12 December 2020

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12 December 2020

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12 December 2020

10.1371/JOURNAL.PONE.0044956

Identifiers

DOI

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13 February 2020

ADS bibcode

2012PLoSO...744956Z

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22984593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

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