Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer (Q28484264)

2

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Susan Cook

3

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Bernard T Golding

4

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Roger J Griffin

5

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Ian R Hardcastle

6

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Lorraine Hewitt

7

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Kety Huberman

8

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Hesta V McNeill

9

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David R Newell

10

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Celine Roche

11

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Claudia A Ryan-Munden

12

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Anna Watson

13

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Craig N Robson

Creative Commons Attribution 4.0 International

14

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language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

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issue

10

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page(s)

e45539

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copyright license

start time

8 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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Tip60 acetylates six lysines of a specific class in core histones in vitro

19 March 2017

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Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60

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19 March 2017

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Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator

19 March 2017

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Tip60 promotes prostate cancer cell proliferation by translocation of androgen receptor into the nucleus

29 September 2017

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Phase II study of the histone deacetylase inhibitor MGCD0103 in patients with previously treated chronic lymphocytic leukaemia

29 September 2017

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Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones.

29 September 2017

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epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

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Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer.

29 September 2017

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Androgen axis in prostate cancer

29 September 2017

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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

29 September 2017

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Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes

29 September 2017

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Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth

29 September 2017

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Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development

29 September 2017

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Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function

29 September 2017

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29 September 2017

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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation

29 September 2017

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29 September 2017

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Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis

2 June 2018

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Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide

2 June 2018

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Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors.

2 June 2018

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Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases.

27 November 2018

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Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466219

Acetylation of the p53 DNA-binding domain regulates apoptosis induction

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466219

Therapeutic effects of PG201, an ethanol extract from herbs, through cartilage protection on collagenase-induced arthritis in rabbits

27 November 2018

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Design, synthesis, and biological evaluation of a small-molecule inhibitor of the histone acetyltransferase Gcn5.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466219

Acetylation of p53 inhibits its ubiquitination by Mdm2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466219

10.1371/JOURNAL.PONE.0045539

27 November 2018

Identifiers

DOI

1 reference

ADS bibcode

2012PLoSO...745539C

0 references

1 reference

1 reference

PubMed publication ID

23056207

1 reference