All four Mycobacterium tuberculosis glnA genes encode glutamine synthetase activities but only GlnA1 is abundantly expressed and essential for bacterial homeostasis (Q28486561)

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English	All four Mycobacterium tuberculosis glnA genes encode glutamine synthetase activities but only GlnA1 is abundantly expressed and essential for bacterial homeostasis	scientific journal article

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scholarly article

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24 January 2017

All four Mycobacterium tuberculosis glnA genes encode glutamine synthetase activities but only GlnA1 is abundantly expressed and essential for bacterial homeostasis (English)

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24 January 2017

Mycobacterium tuberculosis

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author name string

Günter Harth

1

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24 January 2017

Sasa Maslesa-Galić

2

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24 January 2017

Michael V. Tullius

3

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24 January 2017

Marcus A. Horwitz

4

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24 January 2017

language of work or name

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publication date

1 November 2005

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24 January 2017

Molecular Microbiology

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24 January 2017

58

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24 January 2017

4

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24 January 2017

1157–1172

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24 January 2017

Novel subunit-subunit interactions in the structure of glutamine synthetase.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Physical and genetic characterization of the glnA--glnG region of the Escherichia coli chromosome

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

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Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Drug-resistant tuberculosis: review of the worldwide situation and the WHO/IUATLD Global Surveillance Project. International Union Against Tuberculosis and Lung Disease

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

The murI gene of Escherichia coli is an essential gene that encodes a glutamate racemase activity

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

The complete genome sequence of Mycobacterium bovis

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Expression and efficient export of enzymatically active Mycobacterium tuberculosis glutamine synthetase in Mycobacterium smegmatis and evidence that the information for export is contained within the protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

An inhibitor of exported Mycobacterium tuberculosis glutamine synthetase selectively blocks the growth of pathogenic mycobacteria in axenic culture and in human monocytes: extracellular proteins as potential novel drug targets

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21 January 2018

Inhibition of Mycobacterium tuberculosis glutamine synthetase as a novel antibiotic strategy against tuberculosis: demonstration of efficacy in vivo

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Glutamine synthetase of Mycobacterium tuberculosis: extracellular release and characterization of its enzymatic activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-L-glutamate/glutamine cell wall structure, and bacterial replication.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Salmonella typhimurium apparently perceives external nitrogen limitation as internal glutamine limitation

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21 January 2018

A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst

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21 January 2018

Glutamine synthetases of Corynebacterium glutamicum: transcriptional control and regulation of activity

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Global surveillance for antituberculosis-drug resistance, 1994-1997. World Health Organization-International Union against Tuberculosis and Lung Disease Working Group on Anti-Tuberculosis Drug Resistance Surveillance.

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

glnE is an essential gene in Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Expression of glnA in Escherichia coli is regulated at tandem promoters

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Mycothiol Is Essential for Growth ofMycobacterium tuberculosisErdman

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21 January 2018

High extracellular levels of Mycobacterium tuberculosis glutamine synthetase and superoxide dismutase in actively growing cultures are due to high expression and extracellular stability rather than to a protein-specific export mechanism

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Glutamine synthetase GlnA1 is essential for growth of Mycobacterium tuberculosis in human THP-1 macrophages and guinea pigs

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

Suicide substrates for the alanine racemase of Escherichia coli B

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21 January 2018

Catabolic alanine racemase from Salmonella typhimurium: DNA sequence, enzyme purification, and characterization.

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https://api.crossref.org/works/10.1111%2FJ.1365-2958.2005.04899.X

21 January 2018

The genome of the natural genetic engineer Agrobacterium tumefaciens C58

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21 January 2018

Regulation of glutamine synthetase. I. Purification and properties of glutamine synthetase from Escherichia coli.

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21 January 2018

Identifiers

10.1111/J.1365-2958.2005.04899.X

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24 January 2017

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