Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis (Q28486631)

1

1 reference

24 January 2017

A. T. Mangla

2

1 reference

24 January 2017

W. D. Nes

3

1 reference

24 January 2017

M. R. Waterman

Proceedings of the National Academy of Sciences of the United States of America

4

1 reference

24 January 2017

language of work or name

English

0 references

publication date

3 August 1999

1 reference

24 January 2017

1 reference

24 January 2017

96

1 reference

24 January 2017

8937–8942

1 reference

24 January 2017

16

1 reference

24 January 2017

CYP51-like gene of Mycobacterium tuberculosis actually encodes a P450 similar to eukaryotic CYP51

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Mechanism and structural requirements for transformation of substrates by the (S)-adenosyl-L-methionine:delta 24(25)-sterol methyl transferase from Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Site-specific mutations in human ferredoxin that affect binding to ferredoxin reductase and cytochrome P450scc

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Sterol phylogenesis and algal evolution

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Immunopathology of tuberculosis: roles of macrophages and monocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Sterol synergism in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Role of sterols in membranes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Prokaryotic hopanoids and other polyterpenoid sterol surrogates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Plant sterol biosynthesis inhibitors: the 14-demethylation steps, their enzymology and inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Sterol 14 alpha-demethylase and its inhibition: structural considerations on interaction of azole antifungal agents with lanosterol 14 alpha-demethylase (P-450(14DM)) of yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Immunoprecipitation of specific polysomes using Staphylococcus aureus: purification of the immunoglobulin .kappa. chain messenger RNA from the mouse myeloma MPC11

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Identification of the high and low potential flavins of liver microsomal NADPH-cytochrome P-450 reductase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Ferredoxins from two sulfonylurea herbicide monooxygenase systems in Streptomyces griseolus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

A sterol biosynthetic pathway in Mycobacterium.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Flavodoxin and NADPH-flavodoxin reductase from Escherichia coli support bovine cytochrome P450c17 hydroxylase activities.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17711

Steroids and Squalene in Methylococcus capsulatus grown on Methane

27 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Stereochemically distinct roles for sterol in Saccharomycescerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: II. Evolutionary analysis of protein and gene structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Novel sterol transformations promoted by Saccharomyces cerevisiae strain GL7: evidence for 9 beta, 19-cyclopropyl to 9(11)-isomerization and for 14-demethylation to 8(14)-sterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

The structural requirements of sterols for membrane function in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Maximal exponential growth rate and yield of E. coli obtainable in a bench-scale fermentor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Comparison of the chromatographic properties of sterols, select additional steroids and triterpenoids: gravity-flow column liquid chromatography, thin-layer chromatography, gas-liquid chromatography and high-performance liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Oxidation-reduction properties of rat liver cytochromes P-450 and NADPH-cytochrome P-450 reductase related to catalysis in reconstituted systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Plant sterol biosynthesis: novel potent and selective inhibitors of cytochrome P450-dependent obtusifoliol 14 alpha-methyl demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Recombinant human cytochrome P450 1B1 expression in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.16.8937

Structural requirements for transformation of substrates by the (S)-adenosyl-L-methionine:delta 24(25)-sterol methyl transferase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10430874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanistic studies of lanosterol 14 alpha-methyl demethylase: substrate requirements for the component reactions catalyzed by a single cytochrome P-450 isozyme

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10430874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.96.16.8937

1 reference

852126

ADS bibcode

1999PNAS...96.8937B

0 references

852126

1 reference

1 reference

1 reference