Crystal structure and activity studies of the Mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics (Q28487411)

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English	Crystal structure and activity studies of the Mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics	scientific journal article

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scholarly article

1 reference

24 January 2017

Crystal structure and activity studies of the Mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics (English)

1 reference

24 January 2017

antibiotic resistance

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crystal structure

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Mycobacterium tuberculosis

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object named as

Feng Wang

1

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author name string

Craig Cassidy

2

1 reference

24 January 2017

James C. Sacchettini

3

1 reference

24 January 2017

language of work or name

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publication date

1 August 2006

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24 January 2017

Antimicrobial Agents and Chemotherapy

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24 January 2017

50

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24 January 2017

8

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24 January 2017

2762–2771

1 reference

24 January 2017

The CCP4 suite: programs for protein crystallography

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Improved prediction of signal peptides: SignalP 3.0

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19 March 2017

Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure

1 reference

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19 March 2017

Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion

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19 March 2017

Ultrahigh resolution structure of a class A beta-lactamase: on the mechanism and specificity of the extended-spectrum SHV-2 enzyme

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19 March 2017

Acyl-intermediate structures of the extended-spectrum class A beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin, and benzylpenicillin

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19 March 2017

An ultrahigh resolution structure of TEM-1 beta-lactamase suggests a role for Glu166 as the general base in acylation

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19 March 2017

Structure of an extended-spectrum class A beta-lactamase from Proteus vulgaris K1

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Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin

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19 March 2017

Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam

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19 March 2017

Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies

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19 March 2017

Susceptibility of multidrug-resistant strains of Mycobacterium tuberculosis to amoxycillin in combination with clavulanic acid and ethambutol

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19 March 2017

Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution

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19 March 2017

X-ray analysis of the NMC-A beta-lactamase at 1.64-A resolution, a class A carbapenemase with broad substrate specificity

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19 March 2017

Contribution of beta-lactamases to beta-lactam susceptibilities of susceptible and multidrug-resistant Mycobacterium tuberculosis clinical isolates

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Recombinant expression and characterization of the major beta-lactamase of Mycobacterium tuberculosis.

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19 March 2017

Can penicillins and other beta-lactam antibiotics be used to treat tuberculosis?

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A functional classification scheme for beta-lactamases and its correlation with molecular structure

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19 March 2017

beta-Lactamase inhibitors and the inducibility of the beta-lactamase of Mycobacterium tuberculosis

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19 March 2017

Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

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29 September 2017

Characterization of novel Mycobacterium tuberculosis and Mycobacterium smegmatis mutants hypersusceptible to beta-lactam antibiotics.

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29 September 2017

Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity

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29 September 2017

Molecular basis of antibiotic resistance and beta-lactamase inhibition by mechanism-based inactivators: perspectives and future directions

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29 September 2017

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29 September 2017

The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity

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Critical hydrogen bonding by serine 235 for cephalosporinase activity of TEM-1 beta-lactamase

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29 September 2017

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29 September 2017

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29 September 2017

Role of the conserved amino acids of the 'SDN' loop (Ser130, Asp131 and Asn132) in a class A beta-lactamase studied by site-directed mutagenesis

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Interplay of cell wall barrier and beta-lactamase activity determines high resistance to beta-lactam antibiotics in Mycobacterium chelonae

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based on heuristic

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