Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict a risk of drug induced hepatotoxicity (Q28487995)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict a risk of drug induced hepatotoxicity	scientific article

Statements

scholarly article

0 references

Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict a risk of drug induced hepatotoxicity (English)

0 references

1 reference

based on heuristic

inferred from title

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

Katalin Jemnitz

object named as

Katalin Jemnitz

5

author given names

Katalin

author last names

Jemnitz

1 reference

20 October 2023

author name string

Monika Szabo

1

author given names

Monika

author last names

Szabo

1 reference

20 October 2023

Zsuzsa Veres

2

author given names

Zsuzsa

author last names

Veres

1 reference

20 October 2023

Zsolt Baranyai

3

author given names

Zsolt

author last names

Baranyai

1 reference

20 October 2023

Ferenc Jakab

4

author given names

Ferenc

author last names

Jakab

1 reference

20 October 2023

language of work or name

0 references

publication date

2013

0 references

0 references

8

0 references

3

0 references

e59432

0 references

copyright license

Creative Commons Attribution 4.0 International

14 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

19 March 2017

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

19 March 2017

Chapter 4 Preparation of Isolated Rat Liver Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

7 April 2017

The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

The HepaRG cell line: biological properties and relevance as a tool for cell biology, drug metabolism, and virology studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1)by bosentan: a mechanism for species differences in hepatotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Origin and characterization of a human bipotent liver progenitor cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Mechanisms of troglitazone hepatotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Infection of a human hepatoma cell line by hepatitis B virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Drug-induced liver disorders: implications for drug development and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597610

29 September 2017

Xenobiotics inhibit hepatic uptake and biliary excretion of taurocholate in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

Canalicular and sinusoidal disposition of bilirubin mono- and diglucuronides in sandwich-cultured human and rat primary hepatocytes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

Contribution of high basolateral bile salt efflux to the lack of hepatotoxicity in rat in response to drugs inducing cholestasis in human

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

Inhibition of Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake Is the Major Determinant in the Pharmacokinetic Interaction between Bosentan and Cyclosporin A in the Rat

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059432

21 January 2018

Characterization of the transport properties of organic anion transporting polypeptide 1 (oatp1) and Na(+)/taurocholate cotransporting polypeptide (Ntcp): comparative studies on the inhibitory effect of their possible substrates in hepatocytes and c

1 reference

https://pubmed.ncbi.nlm.nih.gov/23516635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity testing in the 21st century: a view from the pharmaceutical industry

1 reference

https://pubmed.ncbi.nlm.nih.gov/23516635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential inhibitory effect of cyclosporin A and bosentan on taurocholate uptake in human and rat hepatocytes as a function of culturing time

1 reference

https://pubmed.ncbi.nlm.nih.gov/23516635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and transport function of drug uptake transporters in differentiated HepaRG cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23516635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug metabolism by the human hepatoma cell, Hep G2

1 reference

https://pubmed.ncbi.nlm.nih.gov/23516635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Taurocholate and Ouabain Transport in Isolated Rat Hepatocytes by Cyclosporin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/23516635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporin, the biology of the bile canaliculus, and cholestasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23516635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporine-induced interference with uptake of bile acids by human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23516635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0059432

0 references

2013PLoSO...859432S

0 references

0 references

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28487995&oldid=1994252091"