Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL (Q28504590)

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

BCL2-related ovarian killer

10 November 2019

main subject

apoptotic process

0 references

1 reference

protein heterodimerization activity

GOA release 2020-03-11

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

N Inohara

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

D Ekhterae

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

I Garcia

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

J Merino

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

A Merry

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

S Chen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

G Núñez

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

English

0 references

publication date

1 April 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

10 November 2019

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

273

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9535847%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

issue

15

2 references

24 January 2017

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10 November 2019

page(s)

8705-8710

1 reference

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Apoptosis in the pathogenesis and treatment of disease

10 November 2019

cites work

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Life, death, and the pursuit of apoptosis.

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

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Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family

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Bcl-x(L) forms an ion channel in synthetic lipid membranes.

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Channel formation by antiapoptotic protein Bcl-2.

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Inhibition of Bax channel-forming activity by Bcl-2

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Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

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Interaction and regulation of subcellular localization of CED-4 by CED-9

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Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9.

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Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

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Induction of apoptosis by the Bcl-2 homologue Bak

21 January 2018

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

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BID: a novel BH3 domain-only death agonist

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Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K

21 January 2018

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harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

21 January 2018

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The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein

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Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

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BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

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Bax-independent inhibition of apoptosis by Bcl-XL.

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Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

21 January 2018

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Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL

21 January 2018

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Bak can accelerate chemotherapy-induced cell death independently of its heterodimerization with Bcl-XL and Bcl-2.

21 January 2018

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CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

21 January 2018

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bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death

21 January 2018

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A rapid and simple method for the isolation of apoptotic DNA fragments.

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Daxx, a novel Fas-binding protein that activates JNK and apoptosis

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21 January 2018

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bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

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