Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease (Q28504767)

24 January 2017

title

Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease (English)

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24 January 2017

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GOA release 2020-03-11

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9

David M. Holtzman

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24 January 2017

8

Bruce J. Aronow

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24 January 2017

Ronald B. DeMattos

1

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24 January 2017

Mark A. O'dell

2

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24 January 2017

Maia Parsadanian

3

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24 January 2017

Jennie W. Taylor

4

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24 January 2017

Judith A. K. Harmony

5

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24 January 2017

Kelly R. Bales

6

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24 January 2017

Steven M. Paul

7

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24 January 2017

language of work or name

English

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publication date

6 August 2002

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Proceedings of the National Academy of Sciences of the United States of America

24 January 2017

published in

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24 January 2017

volume

99

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24 January 2017

issue

16

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24 January 2017

page(s)

10843–10848

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Intrinsically disordered protein

24 January 2017

cites work

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Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state

19 March 2017

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Clusterin, a binding protein with a molten globule-like region

19 March 2017

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19 March 2017

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29 September 2017

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Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis

29 September 2017

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29 September 2017

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29 September 2017

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Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

29 September 2017

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29 September 2017

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29 September 2017

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Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

29 September 2017

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Clusterin (Apo J) protects against in vitro amyloid-beta (1-40) neurotoxicity

29 September 2017

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29 September 2017

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Apolipoprotein J expression at fluid-tissue interfaces: potential role in barrier cytoprotection

29 September 2017

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Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat.

29 September 2017

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Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration

29 September 2017

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Apolipoproteins in human cerebrospinal fluid

29 September 2017

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Nascent astrocyte particles differ from lipoproteins in CSF.

29 September 2017

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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

2 June 2018

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2 June 2018

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Apolipoprotein J and Alzheimer's amyloid beta solubility

2 June 2018

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The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

2 June 2018

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Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta

2 June 2018

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2 June 2018

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Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

2 June 2018

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Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice

27 November 2018

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Statistical aspects of quantitative image analysis of beta-amyloid in the APP(V717F) transgenic mouse model of Alzheimer's disease

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125060

Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125060

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125060

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125060

Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125060

Pathogenic effects of D23N Iowa mutant amyloid beta -protein

27 November 2018

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12 December 2020

Characterization of subpopulations of lipoprotein particles isolated from human cerebrospinal fluid

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12 December 2020

Characterization of apolipoprotein J-Alzheimer's A beta interaction

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12 December 2020

Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock Proteins

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12 December 2020

Identifiers

DOI

10.1073/PNAS.162228299

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ADS bibcode

2002PNAS...9910843D

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