Histone deacetylase inhibitor MS-275 stimulates bone formation in part by enhancing Dhx36-mediated TNAP transcription (Q28505369)

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1 February 2020

title

Histone deacetylase inhibitor MS-275 stimulates bone formation in part by enhancing Dhx36-mediated TNAP transcription (English)

2 references

24 January 2017

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1 February 2020

main subject

Histone deacetylase 4

1 reference

DEAH (Asp-Glu-Ala-His) box polypeptide 36

GOA release 2020-03-11

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GOA release 2020-03-11

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6

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author name string

Ha-Neui Kim

1

2 references

24 January 2017

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1 February 2020

Jong-Ho Lee

2

2 references

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1 February 2020

Suk-Chul Bae

3

2 references

24 January 2017

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1 February 2020

Hyun-Mo Ryoo

4

2 references

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Hong-Hee Kim

5

2 references

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1 February 2020

Zang Hee Lee

7

2 references

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publication date

1 September 2011

2 references

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Journal of Bone and Mineral Research

1 February 2020

published in

2 references

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volume

26

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issue

9

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page(s)

2161-2173

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Therapeutic approaches to bone diseases

1 February 2020

cites work

1 reference

Osteoclast-targeting small molecules for the treatment of neoplastic bone metastases

21 January 2018

1 reference

TNAP, TrAP, ecto-purinergic signaling, and bone remodeling

21 January 2018

1 reference

Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders

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Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

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Cbfa1 isoforms exert functional differences in osteoblast differentiation

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Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2

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Anticancer activities of histone deacetylase inhibitors

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The many roles of histone deacetylases in development and physiology: implications for disease and therapy

21 January 2018

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Chemical phylogenetics of histone deacetylases

21 January 2018

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Identification of novel isoform-selective inhibitors within class I histone deacetylases

21 January 2018

1 reference

MS-275, a potent orally available inhibitor of histone deacetylases--the development of an anticancer agent

21 January 2018

1 reference

Histone deacetylase 1-mediated histone modification regulates osteoblast differentiation.

21 January 2018

1 reference

Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation

21 January 2018

1 reference

Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner

21 January 2018

1 reference

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

21 January 2018

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Bone morphogenetic protein-2 stimulates Runx2 acetylation

21 January 2018

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Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

21 January 2018

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Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice.

21 January 2018

1 reference

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat

21 January 2018

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Epigenetic control of skull morphogenesis by histone deacetylase 8

21 January 2018

1 reference

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

21 January 2018

1 reference

Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally

21 January 2018

1 reference

Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors

21 January 2018

1 reference

Histone deacetylase inhibitors promote osteoblast maturation

21 January 2018

1 reference

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts.

21 January 2018

1 reference

Adverse effects of valproate on bone: defining a model to investigate the pathophysiology

21 January 2018

1 reference

Evaluation of pharmaceuticals with a novel 50-hour animal model of bone loss.

21 January 2018

1 reference

Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling

21 January 2018

1 reference

The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

21 January 2018

1 reference

SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1.

21 January 2018

1 reference

The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner

21 January 2018

1 reference

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

21 January 2018

1 reference

HDAC4 deacetylase associates with and represses the MEF2 transcription factor

21 January 2018

1 reference

Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL.

21 January 2018

1 reference

Inhibition of histone deacetylase suppresses osteoclastogenesis and bone destruction by inducing IFN-beta production

21 January 2018

1 reference

Di-n-propylacetate and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase

21 January 2018

1 reference

Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU

21 January 2018

1 reference

Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.

21 January 2018

1 reference

The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates

21 January 2018

1 reference

DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation

21 January 2018

1 reference

A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA

21 January 2018

1 reference

The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor

21 January 2018

1 reference

The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation

21 January 2018

1 reference

p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation

21 January 2018

1 reference

A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.

21 January 2018

1 reference

Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor

21 January 2018

1 reference

The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

21 January 2018

1 reference

MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells

21 January 2018

1 reference

The induction of bone formation in rat calvarial defects and subcutaneous tissues by recombinant human BMP-2, produced in Escherichia coli

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JBMR.426

2 references

Consolidated OpenCitations Corpus – April 2017

3749972

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1 February 2020

3749972

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

3749972