PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures (Q28505640)

GOA release 2020-03-11

1 reference

Colin Farquharson

9

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Richard M. Aspden

object named as

Richard M. Aspden

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author name string

Carmen Huesa

1

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24 January 2017

Manisha C. Yadav

2

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24 January 2017

Mikko A. J. Finnilä

3

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24 January 2017

Simon R. Goodyear

4

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24 January 2017

Simon P. Robins

5

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24 January 2017

K. Elizabeth Tanner

6

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24 January 2017

José Luis Millán

describes a project that uses

8

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24 January 2017

1 May 2011

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24 January 2017

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24 January 2017

48

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24 January 2017

5

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24 January 2017

1066–1074

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24 January 2017

ImageJ

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3078982/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcification

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Kinetic analysis of substrate utilization by native and TNAP-, NPP1-, or PHOSPHO1-deficient matrix vesicles

19 March 2017

1 reference

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The presence of PHOSPHO1 in matrix vesicles and its developmental expression prior to skeletal mineralization

19 March 2017

1 reference

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Human PHOSPHO1 exhibits high specific phosphoethanolamine and phosphocholine phosphatase activities

19 March 2017

1 reference

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Role of the mouse ank gene in control of tissue calcification and arthritis

19 March 2017

1 reference

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Inhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chick

19 March 2017

1 reference

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Role of matrix vesicles in biomineralization

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The use of nanoindentation for characterizing the properties of mineralized hard tissues: state-of-the art review

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Collagen/annexin V interactions regulate chondrocyte mineralization

29 September 2017

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Functional involvement of PHOSPHO1 in matrix vesicle-mediated skeletal mineralization.

29 September 2017

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The role of matrix vesicles in growth plate development and biomineralization

29 September 2017

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Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders

29 September 2017

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Mechanisms of osteoporosis therapy: a bone strength perspective

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Comparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily.

29 September 2017

1 reference

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Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient mice

29 September 2017

1 reference

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Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization

29 September 2017

1 reference

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Biomechanics of bone: determinants of skeletal fragility and bone quality

29 September 2017

1 reference

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Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia

29 September 2017

1 reference

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Identification and cloning of a novel phosphatase expressed at high levels in differentiating growth plate chondrocytes.

29 September 2017

1 reference

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Matrix vesicles in osteomalacic hypophosphatasia bone contain apatite-like mineral crystals

29 September 2017

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Function of osteocytes in bone--their role in mechanotransduction

29 September 2017

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Association of inorganic-pyrophosphatase activity with human alkaline-phosphatase preparations

29 September 2017

1 reference

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The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures

29 September 2017

1 reference

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Studies on matrix vesicles isolated from chick epiphyseal cartilage Association of pyrophosphatase and ATPase activities with alkaline phosphatase

29 September 2017

1 reference

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Inorganic pyrophosphatase induces type I collagen in osteoblasts

29 September 2017

1 reference

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Enhanced expression of the inorganic phosphate transporter Pit-1 is involved in BMP-2-induced matrix mineralization in osteoblast-like cells.

2 June 2018

1 reference

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Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2.

2 June 2018

1 reference

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Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone

2 June 2018

1 reference

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Collagen cross-links in mineralizing tissues: a review of their chemistry, function, and clinical relevance

2 June 2018

1 reference

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Chemistry of collagen cross-linking: biochemical changes in collagen during the partial mineralization of turkey leg tendon

2 June 2018

1 reference

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Reduced concentrations of collagen cross-links are associated with reduced strength of bone.

2 June 2018

1 reference

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Mineralization in the chick embryo. I. Monohydrogen phosphate and carbonate relationships during maturation of the bone crystal complex

2 June 2018

1 reference

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Decreased trabecular width and increased trabecular spacing contribute to bone loss with aging.

2 June 2018

1 reference

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Bone histomorphometry: standardization of nomenclature, symbols and units (summary of proposed system).

2 June 2018

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Quantification of immature and mature collagen crosslinks by liquid chromatography-electrospray ionization mass spectrometry in connective tissues

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on bone material properties

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

Deformation partitioning provides insight into elastic, plastic, and viscous contributions to bone material behavior.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

Genetic selection for fast growth generates bone architecture characterised by enhanced periosteal expansion and limited consolidation of the cortices but a diminution in the early responses to mechanical loading.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

A comparison of cortical and trabecular bone from C57 Black 6 mice using Raman spectroscopy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

The degree of mineralization is a determinant of bone strength: a study on human calcanei.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

27 November 2018

1 reference

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Mechanical properties of adult vertebral cancellous bone: correlation with collagen intermolecular cross-links

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

Changes in phospholipid extractability and composition accompany mineralization of chicken growth plate cartilage matrix vesicles

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078982

Association of PLOD1 polymorphisms with bone mineral density in a population-based study of women from the UK

27 November 2018

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12 December 2020

Can biological calcification occur in the presence of pyrophosphate?

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12 December 2020

The determination of total hydroxyproline in urine and bone extracts

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12 December 2020

The strength of a calcified tissue depends in part on the molecular structure and organization of its constituent mineral crystals in their organic matrix

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12 December 2020

In vivo fatigue microcracks in human bone: Material properties of the surrounding bone matrix

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12 December 2020

Causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular inorganic pyrophosphate generation demonstrated by transfection of cultured fibroblasts and osteoblasts with plasma cell membrane glycoprotein-1. Relevance

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12 December 2020

THE PHENOMENA OF EARLY STAGES IN BONE REPAIR

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12 December 2020

Physical characteristics affecting the tensile failure properties of compact bone

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12 December 2020

Quantitative analysis of the pyridinium crosslinks of collagen in urine using ion-paired reversed-phase high-performance liquid chromatography

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12 December 2020

Hereditary joint disorder in progressive ankylosis (ank/ank) mice I. association of calcium hydroxyapatite deposition with inflammatory arthropathy

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12 December 2020

BAPN dose dependence of mature crosslinking in bone matrix collagen of rabbit compact bone: corresponding variation of sonic velocity and equatorial diffraction spacing

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12 December 2020

Mechanical testing of bone ex vivo

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12 December 2020

Micro-Raman line broadening in synthetic carbonated hydroxyapatite

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12 December 2020

10.1016/J.BONE.2011.01.010

Identifiers

DOI

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4458160

4458160

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1 reference

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