High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease (Q28505711)

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English	High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease	scientific journal article

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scholarly article

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24 January 2017

High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease (English)

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24 January 2017

Ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)

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GOA release 2020-03-11

neurotransmitter

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based on heuristic

inferred from title

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based on heuristic

inferred from title

nmr-based metabolomics

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based on heuristic

inferred from title

author name string

Michael R. Pears

1

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24 January 2017

Jonathan D. Cooper

2

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24 January 2017

Hannah M. Mitchison

3

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24 January 2017

Russell J. Mortishire-Smith

4

1 reference

24 January 2017

David A. Pearce

5

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24 January 2017

Julian L. Griffin

6

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24 January 2017

language of work or name

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publication date

30 December 2005

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24 January 2017

Journal of Biological Chemistry

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24 January 2017

280

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24 January 2017

42508–42514

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24 January 2017

52

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24 January 2017

Evidence for lipase abnormality: high levels of free and triacylglycerol forms of unsaturated fatty acids in neuronal ceroid-lipofuscinosis tissue.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Selectivity and types of cell death in the neuronal ceroid lipofuscinoses

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Neurodegenerative disease: the neuronal ceroid lipofuscinoses (Batten disease).

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Pheno/genotypic correlations of neuronal ceroid lipofuscinoses

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

The relationship between lipofuscin pigment and ageing in the human nervous system

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

The genetic spectrum of human neuronal ceroid-lipofuscinoses

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Progress towards understanding the neurobiology of Batten disease or neuronal ceroid lipofuscinosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Targeted disruption of the Cln3 gene provides a mouse model for Batten disease. The Batten Mouse Model Consortium [corrected]

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Vitamin E deficiency and metabolic deficits in neuronal ceroid lipofuscinosis described by bioinformatics.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Automatic reduction of NMR spectroscopic data for statistical and pattern recognition classification of samples

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

An autoantibody inhibitory to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Glutamine Synthetase: Glial Localization in Brain

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Functional categorization of gene expression changes in the cerebellum of a Cln3-knockout mouse model for Batten disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Early changes in gene expression in two models of Batten disease.

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Glutamine synthetase and glutamate dehydrogenase in the prefrontal cortex of patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Glutamate-glutamine cycling in the epileptic human hippocampus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Osmotic regulation of myo-inositol uptake in primary astrocyte cultures.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Microglia: a sensor for pathological events in the CNS

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https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Reactive microgliosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Late onset neurodegeneration in the Cln3-/- mouse model of juvenile neuronal ceroid lipofuscinosis is preceded by low level glial activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Hypo-osmotic swelling-activated release of organic osmolytes in brain slices: implications for brain oedema in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Magnetic resonance spectroscopy of the human brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Proton spectroscopic imaging shows abnormalities in glial and neuronal cell pools in frontal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

A role in vacuolar arginine transport for yeast Btn1p and for human CLN3, the protein defective in Batten disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Interaction among Btn1p, Btn2p, and Ist2p reveals potential interplay among the vacuole, amino acid levels, and ion homeostasis in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

N-Acetyl-<i>L</i>-Aspartate is a Major Source of Acetyl Groups for Lipid Synthesis during Rat Brain Development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Synthesis of N-acetyl-l-aspartate by rat brain mitochondria and its involvement in mitochondrial/cytosolic carbon transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Decreased brain N-acetylaspartate in Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Reduced brain N-acetylaspartate suggests neuronal loss in cognitively impaired human immunodeficiency virus-seropositive individuals: in vivo 1H magnetic resonance spectroscopic imaging

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

N-acetyl-L-aspartate and other amino acid metabolites in Alzheimer's disease brain: a preliminary proton nuclear magnetic resonance study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507380200

21 January 2018

A mouse model for Finnish variant late infantile neuronal ceroid lipofuscinosis, CLN5, reveals neuropathology associated with early aging

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M507380200

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1 reference

24 January 2017

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