Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation (Q28505847)

24 January 2017

title

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation (English)

1 reference

Notum palmitoleoyl-protein carboxylesterase

24 January 2017

main subject

1 reference

GOA release 2020-03-11

E. Yvonne Jones

7

0 references

author name string

Xinjun Zhang

1

1 reference

24 January 2017

Seong-Moon Cheong

2

1 reference

24 January 2017

Nathalia G. Amado

3

1 reference

24 January 2017

Alice H. Reis

4

1 reference

24 January 2017

Bryan T. MacDonald

5

1 reference

24 January 2017

Matthias Zebisch

6

1 reference

24 January 2017

Jose Garcia Abreu

8

1 reference

24 January 2017

Xi He

9

1 reference

24 January 2017

language of work or name

English

0 references

publication date

23 March 2015

1 reference

24 January 2017

1 reference

24 January 2017

volume

32

1 reference

24 January 2017

issue

6

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24 January 2017

page(s)

719–730

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Notum deacylates Wnt proteins to suppress signalling activity

24 January 2017

cites work

1 reference

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Identification of key residues and regions important for porcupine-mediated Wnt acylation

19 March 2017

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Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation

19 March 2017

1 reference

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Wnt/β-catenin signaling and disease

19 March 2017

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Structural basis of Wnt recognition by Frizzled

19 March 2017

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Wnt/beta-catenin signaling: components, mechanisms, and diseases

19 March 2017

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19 March 2017

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Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

19 March 2017

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Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion

19 March 2017

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Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus

19 March 2017

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HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient

19 March 2017

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Alpha/beta hydrolase fold enzymes: the family keeps growing

19 March 2017

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Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo

19 March 2017

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Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis

19 March 2017

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Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern

19 March 2017

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Wnt proteins are lipid-modified and can act as stem cell growth factors

19 March 2017

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Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

7 April 2017

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Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins

7 April 2017

1 reference

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Neural induction and early patterning in vertebrates.

29 September 2017

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Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling

29 September 2017

1 reference

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Secreted and transmembrane wnt inhibitors and activators

29 September 2017

1 reference

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Wnt signaling in vertebrate axis specification

29 September 2017

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Precise regulation of porcupine activity is required for physiological Wnt signaling.

29 September 2017

1 reference

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A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway

29 September 2017

1 reference

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Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Roles of N-glycosylation and lipidation in Wg secretion and signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Porcupine-mediated lipidation is required for Wnt recognition by Wls.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Profiling cellular myristoylation and palmitoylation using ω-alkynyl fatty acids

29 September 2017

1 reference

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Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome

29 September 2017

1 reference

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WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

29 September 2017

1 reference

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Shaping morphogen gradients by proteoglycans

29 September 2017

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BMP inhibition initiates neural induction via FGF signaling and Zic genes.

29 September 2017

1 reference

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Protein acyl thioesterases (Review).

29 September 2017

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Glypican-mediated endocytosis of Hedgehog has opposite effects in flies and mice

29 September 2017

1 reference

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Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a

29 September 2017

1 reference

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Helping Wingless take flight: how WNT proteins are secreted

29 September 2017

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A balance of FGF, BMP and WNT signalling positions the future placode territory in the head

29 September 2017

1 reference

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Neural induction: old problem, new findings, yet more questions

29 September 2017

1 reference

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Dorsal-ventral patterning and neural induction in Xenopus embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Wingful, an extracellular feedback inhibitor of Wingless

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Notum homolog plays a novel role in primary motor innervation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Polarized notum activation at wounds inhibits Wnt function to promote planarian head regeneration

2 June 2018

1 reference

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Formation and function of Spemann's organizer

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Direct and long-range action of a wingless morphogen gradient

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Fates of the blastomeres of the 32-cell-stage Xenopus embryo

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Patterning and growth control by membrane-tethered Wingless.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375027

A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus.

27 November 2018

1 reference

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The status of Wnt signalling regulates neural and epidermal fates in the chick embryo

27 November 2018

1 reference

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Initiation of neural induction by FGF signalling before gastrulation.

27 November 2018

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bFGF as a possible morphogen for the anteroposterior axis of the central nervous system in Xenopus.

27 November 2018

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Wingless gradient formation in the Drosophila wing

27 November 2018

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12 December 2020

Glypican-3 binds to Frizzled and plays a direct role in the stimulation of canonical Wnt signaling

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12 December 2020

Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition

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12 December 2020

An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo

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12 December 2020

Fate map for the 32-cell stage of Xenopus laevis

1 reference

12 December 2020

Neural induction in Xenopus requires inhibition of Wnt-beta-catenin signaling

1 reference

12 December 2020