Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects (Q28506220)

Activin A receptor, type 1

GOA release 2020-03-11

1 reference

Transforming growth factor, beta receptor I

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

6

0 references

author name string

Jikui Wang

1

1 reference

24 January 2017

Andre Nagy

2

1 reference

24 January 2017

Jonas Larsson

3

1 reference

24 January 2017

Marek Dudas

4

1 reference

24 January 2017

Henry M. Sucov

BMC Developmental Biology

5

1 reference

24 January 2017

1 November 2006

1 reference

24 January 2017

1 reference

24 January 2017

6

1 reference

24 January 2017

51

1 reference

24 January 2017

https://scigraph.springernature.com/pub.10.1186/1471-213x-6-51

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Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells

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Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract

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BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium

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Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

19 March 2017

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Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects

19 March 2017

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Altered apoptosis pattern during pharyngeal arch artery remodelling is associated with aortic arch malformations in Tgfbeta2 knock-out mice

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29 September 2017

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29 September 2017

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2 June 2018

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GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation.

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27 November 2018

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27 November 2018

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27 November 2018

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