Disregulated RhoGTPases and Actin Cytoskeleton Contribute to the Migration Defect in Lis1-Deficient Neurons (Q28507967)

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12 May 2020

Disregulated RhoGTPases and Actin Cytoskeleton Contribute to the Migration Defect in Lis1-Deficient Neurons (English)

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https://api.crossref.org/works/10.1523/JNEUROSCI.23-25-08673.2003

14 March 2024

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Platelet-activating factor acetylhydrolase, isoform 1b, subunit 1

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GOA release 2020-03-11

author

Anthony Wynshaw-Boris

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author name string

Stanislav S. Kholmanskikh

1

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Joseph S. Dobrin

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Paul C. Letourneau

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M. Elizabeth Ross

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full work available at URL

14 March 2024

language of work or name

English

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publication date

24 September 2003

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24 January 2017

http://www.jneurosci.org/content/jneuro/23/25/8673.full.pdf

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Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507966

http://www.jneurosci.org/cgi/content/abstract/23/25/8673

14 March 2024

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https://europepmc.org/articles/PMC6740411

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https://doi.org/10.1523/jneurosci.23-25-08673.2003

14 March 2024

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published in

Journal of Neuroscience

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24 January 2017

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volume

23

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issue

25

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12 May 2020

page(s)

8673-8681

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Effectors for the Rho GTPases

12 May 2020

cites work

1 reference

12 December 2020

Central nervous system neuronal migration

1 reference

12 December 2020

Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous

1 reference

12 December 2020

Doublecortin, a stabilizer of microtubules

1 reference

12 December 2020

LIS1 is a microtubule-associated phosphoprotein

1 reference

12 December 2020

Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts

1 reference

12 December 2020

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

12 December 2020

Signaling to Rho GTPases

1 reference

12 December 2020

Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion

1 reference

12 December 2020

The role of cytoplasmic dynein in the human brain developmental disease lissencephaly

1 reference

12 December 2020

Rho GTPases and their effector proteins

1 reference

12 December 2020

A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons

1 reference

12 December 2020

Regulating actin dynamics in neuronal growth cones by ADF/cofilin and rho family GTPases

1 reference

12 December 2020

Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE

1 reference

12 December 2020

Interaction between LIS1 and doublecortin, two lissencephaly gene products

1 reference

12 December 2020

Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1

1 reference

12 December 2020

Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.

1 reference

12 December 2020

A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function

1 reference

12 December 2020

Rho GTPases: signaling, migration, and invasion

1 reference

12 December 2020

LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome

1 reference

12 December 2020

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

1 reference

12 December 2020

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

1 reference

12 December 2020

p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion.

1 reference

12 December 2020

NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins

1 reference

12 December 2020

LIS1 and dynein motor function in neuronal migration and development

1 reference

12 December 2020

RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway

1 reference

12 December 2020

The Aspergillus cytoplasmic dynein heavy chain and NUDF localize to microtubule ends and affect microtubule dynamics.

1 reference

12 December 2020

Protein-protein interactions, cytoskeletal regulation and neuronal migration

1 reference

12 December 2020

Human brain malformations and their lessons for neuronal migration

1 reference

12 December 2020

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

1 reference

12 December 2020

Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway.

1 reference

12 December 2020

Cell motility: can Rho GTPases and microtubules point the way?

1 reference

12 December 2020

Regulation of rho GTPases by crosstalk and neuronal activity in vivo.

1 reference

12 December 2020

Guanine nucleotide-dependent ADP-ribosylation of soluble rho catalyzed by Clostridium botulinum C3 ADP-ribosyltransferase. Isolation and characterization of a newly recognized form of rhoA.

1 reference

12 December 2020

Neuron-glia interactions of rat hippocampal cells in vitro: glial-guided neuronal migration and neuronal regulation of glial differentiation.

1 reference

12 December 2020

Glial-guided granule neuron migration in vitro: a high-resolution time-lapse video microscopic study

1 reference

12 December 2020

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

12 December 2020

Motility and cytoskeletal organization of migrating cerebellar granule neurons

1 reference

12 December 2020

Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]

1 reference

12 December 2020

Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats

1 reference

12 December 2020

Cell migration: a physically integrated molecular process

1 reference

12 December 2020

Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit.

1 reference

12 December 2020

Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer

1 reference

12 December 2020

Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

1 reference

12 December 2020

Direct evidence for homotypic, glia-independent neuronal migration.

1 reference

12 December 2020

The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

1 reference

12 December 2020

Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit.

1 reference

12 December 2020

Platelet-activating factor receptor stimulation disrupts neuronal migration In vitro.

1 reference

12 December 2020

Distinct modes of neuronal migration in different domains of developing cerebellar cortex.

1 reference

12 December 2020

The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC

1 reference

12 December 2020

Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality

1 reference

12 December 2020

Microtubule depolymerization induces stress fibers, focal adhesions, and DNA synthesis via the GTP-binding protein Rho.

1 reference

12 December 2020

Nuclear migration, nucleokinesis and lissencephaly.

1 reference

12 December 2020

Signaling to the actin cytoskeleton

1 reference

12 December 2020

Rho GTPases and their effector proteins

3

1 reference

https://api.crossref.org/works/10.1523/JNEUROSCI.23-25-08673.2003

Imaging physiologic dysfunction of individual hippocampal subregions in humans and genetically modified mice.

14 March 2024

11

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https://api.crossref.org/works/10.1523/JNEUROSCI.23-25-08673.2003

14 March 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740411&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740411&resulttype=core&format=json

12 May 2020

2 references

24 January 2017