Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells (Q28508125)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18625844%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells (English)

2 references

24 January 2017

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Poly(A) binding protein, cytoplasmic 1

10 January 2020

main subject

1 reference

PAN2 poly(A) specific ribonuclease subunit

1 reference

GTPase activating protein (SH3 domain) binding protein 1

1 reference

PAN3 poly(A) specific ribonuclease subunit

1 reference

Decapping mRNA 1A

1 reference

Nocturnin

1 reference

5'-3' exoribonuclease 1

1 reference

CCR4-NOT transcription complex, subunit 7

1 reference

author

Dinghai Zheng

1

1 reference

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10 January 2020

author name string

Nader Ezzeddine

2

2 references

24 January 2017

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10 January 2020

Wenmiao Zhu

4

2 references

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10 January 2020

Xiangwei He

5

2 references

24 January 2017

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10 January 2020

Ann-Bin Shyu

6

2 references

24 January 2017

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10 January 2020

Chyi-Ying A Chen

3

1 reference

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10 January 2020

language of work or name

English

0 references

publication date

1 July 2008

1 reference

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10 January 2020

published in

Journal of Cell Biology

2 references

24 January 2017

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10 January 2020

volume

182

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10 January 2020

issue

1

2 references

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10 January 2020

page(s)

89-101

1 reference

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describes a project that uses

10 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2447901/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Poly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding protein

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TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements

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P bodies: at the crossroads of post-transcriptional pathways

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mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

19 March 2017

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Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

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A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay

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Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

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Conservation of the deadenylase activity of proteins of the Caf1 family in human

19 March 2017

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UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant

19 March 2017

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Cytoplasmic foci are sites of mRNA decay in human cells

19 March 2017

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Identification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein

19 March 2017

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The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies

19 March 2017

1 reference

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Functional characterization of the mammalian mRNA decapping enzyme hDcp2

19 March 2017

1 reference

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Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway

19 March 2017

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Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

19 March 2017

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19 March 2017

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Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay

19 March 2017

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The hDcp2 protein is a mammalian mRNA decapping enzyme

19 March 2017

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Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

19 March 2017

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Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding

19 March 2017

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The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

19 March 2017

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The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

19 March 2017

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A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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P bodies and the control of mRNA translation and degradation

19 March 2017

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MicroRNAs direct rapid deadenylation of mRNA

7 April 2017

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General translational repression by activators of mRNA decapping

7 April 2017

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The enzymes and control of eukaryotic mRNA turnover

7 April 2017

1 reference

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RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

7 April 2017

1 reference

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7 April 2017

1 reference

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An essential component of the decapping enzyme required for normal rates of mRNA turnover

7 April 2017

1 reference

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Premature translational termination triggers mRNA decapping

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447901

Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules

7 April 2017

1 reference

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Mammalian stress granules and processing bodies

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447901

GW182 family proteins are crucial for microRNA-mediated gene silencing

29 September 2017

1 reference

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Versatile applications of transcriptional pulsing to study mRNA turnover in mammalian cells

29 September 2017

1 reference

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Analysis of P-body assembly in Saccharomyces cerevisiae

29 September 2017

1 reference

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Mechanisms of microRNA-mediated gene regulation in animal cells

29 September 2017

1 reference

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Probing the mRNA processing body using protein macroarrays and "autoantigenomics".

29 September 2017

1 reference

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How do microRNAs regulate gene expression?

29 September 2017

1 reference

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Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447901

ARE-mRNA degradation requires the 5'-3' decay pathway.

29 September 2017

1 reference

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A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447901

Positive and negative regulation of poly(A) nuclease

29 September 2017

1 reference

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Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element

29 September 2017

1 reference

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A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy

29 September 2017

1 reference

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P-body formation is a consequence, not the cause, of RNA-mediated gene silencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447901

Transcriptional pulsing approaches for analysis of mRNA turnover in mammalian cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447901

Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447901

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447901

Evidence that microRNAs are associated with translating messenger RNAs in human cells

2 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200801196

C. elegans homologue of the Caf1 gene, which encodes a subunit of the CCR4-NOT complex, is essential for embryonic and larval development and for meiotic progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200801196

Mouse CAF1 can function as a processive deadenylase/3'-5'-exonuclease in vitro but in yeast the deadenylase function of CAF1 is not required for mRNA poly(A) removal

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200801196

21 January 2018

Identifiers

DOI

10.1083/JCB.200801196

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18625844%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18625844%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

2 references