GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier (Q28509184)

GOA release 2020-03-11

17

Lino Tessarollo

1 reference

24 January 2017

Mike Cullen

1

1 reference

24 January 2017

Mohammed K. Elzarrad

2

1 reference

24 January 2017

Steven Seaman

3

1 reference

24 January 2017

Enrique Zudaire

4

1 reference

24 January 2017

Janine Stevens

5

1 reference

24 January 2017

Mi Young Yang

6

1 reference

24 January 2017

Xiujie Li

7

1 reference

24 January 2017

Amit Chaudhary

8

1 reference

24 January 2017

Lihong Xu

9

1 reference

24 January 2017

Mary Beth Hilton

10

1 reference

24 January 2017

Daniel Logsdon

11

1 reference

24 January 2017

Emily Hsiao

12

1 reference

24 January 2017

Erica V. Stein

13

1 reference

24 January 2017

Frank Cuttitta

14

1 reference

24 January 2017

Diana C. Haines

15

1 reference

24 January 2017

Kunio Nagashima

16

1 reference

24 January 2017

Brad St Croix

Proceedings of the National Academy of Sciences of the United States of America

18

1 reference

24 January 2017

language of work or name

English

0 references

publication date

5 April 2011

1 reference

24 January 2017

1 reference

24 January 2017

108

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24 January 2017

5759–5764

1 reference

24 January 2017

14

1 reference

24 January 2017

Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

19 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

PV1 is a key structural component for the formation of the stomatal and fenestral diaphragms

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Cell surface tumor endothelial markers are conserved in mice and humans

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Genes expressed in human tumor endothelium

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

The blood-brain barrier in health and chronic neurodegenerative disorders

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Angiogenesis as a therapeutic target

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Role of vasodilator stimulated phosphoprotein in VEGF induced blood-brain barrier permeability in endothelial cell monolayers

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Diverse roles of the vasculature within the neural stem cell niche

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Understanding the blood-brain barrier using gene and protein expression profiling technologies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Cell-based assays in GPCR drug discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Plasmalemmal vesicle associated protein-1 (PV-1) is a marker of blood-brain barrier disruption in rodent models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Genes that distinguish physiological and pathological angiogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Blood-brain barrier delivery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

An in vitro assay reveals a role for the diaphragm protein PV-1 in endothelial fenestra morphogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

beta8 integrins are required for vascular morphogenesis in mouse embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Glomeruloid microvascular proliferation follows adenoviral vascular permeability factor/vascular endothelial growth factor-164 gene delivery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

PV-1 is a component of the fenestral and stomatal diaphragms in fenestrated endothelia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. Studies with quantitative western blotting and in situ hybridization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Increased blood-brain barrier permeability and endothelial abnormalities induced by vascular endothelial growth factor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Glomeruloid vascular structures in glioblastoma multiforme: an immunohistochemical and ultrastructural study

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Ontogenic expression of the erythroid-type glucose transporter (Glut 1) in the telencephalon of the mouse: correlation to the tightening of the blood-brain barrier.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Congenital Hydrocephalus-Hydrencephaly in Five Siblings, with Autopsy Studies: a New Disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Glomeruloid Structures as Vascular Reaction in Human Gastrointestinal Carcinoma

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1017192108

TGFbeta1 and TGFbeta3 are partially redundant effectors in brain vascular morphogenesis.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1017192108

Induction of focal angiogenesis through adenoviral vector mediated vascular endothelial cell growth factor gene transfer in the mature mouse brain

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1017192108

Hypoxia induces permeability in brain microvessel endothelial cells via VEGF and NO.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078373

VEGF-A angiogenesis induces a stable neovasculature in adult murine brain

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21421844

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1017192108

1 reference

85182

ADS bibcode

2011PNAS..108.5759C

0 references

85182

1 reference

1 reference

1 reference