Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis (Q28509293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19139395%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19139395%20AND%20SRC:MED&resulttype=core&format=json

High mobility group box 2

19 January 2020

main subject

osteoarthritis

0 references

1 reference

GOA release 2020-03-11

1 reference

2

1 reference

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19 January 2020

Marco E. Bianchi

6

1 reference

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19 January 2020

author name string

Noboru Taniguchi

1

2 references

24 January 2017

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19 January 2020

Lorenza Ronfani

3

2 references

24 January 2017

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19 January 2020

Ulrich Ulmer

4

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19139395%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Setsuro Komiya

5

2 references

24 January 2017

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19 January 2020

Martin Lotz

7

2 references

24 January 2017

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19 January 2020

language of work or name

English

0 references

publication date

12 January 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19139395%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

2 references

24 January 2017

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19 January 2020

volume

106

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24 January 2017

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19 January 2020

page(s)

1181-1186

1 reference

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19 January 2020

issue

4

2 references

24 January 2017

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The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth

19 January 2020

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Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation

19 March 2017

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Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2

19 March 2017

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The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2

19 March 2017

1 reference

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The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice

19 March 2017

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High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells

19 March 2017

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HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation

19 March 2017

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Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification

19 March 2017

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Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.

29 September 2017

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Risk factors and prognostic factors of hip and knee osteoarthritis

29 September 2017

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Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

29 September 2017

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Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function

29 September 2017

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The surface of articular cartilage contains a progenitor cell population

29 September 2017

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HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma

29 September 2017

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HMGB proteins and gene expression

29 September 2017

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Mitotic misregulation and human aging

29 September 2017

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Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and Is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism.

29 September 2017

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Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data

29 September 2017

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Cell Counts of Normal and Osteo-Arthritic Articular Cartilage in Relation to the Uptake of Sulphate (35SO4) in vitro

29 September 2017

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ADP-ribosylation of HMG proteins and its modulation by different effectors in the liver of aging rats

2 June 2018

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The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study

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Age- and site-associated biomechanical weakening of human articular cartilage of the femoral condyle

21 January 2018

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The effect of glycosaminoglycan loss on chondrocyte viability: a study on porcine cartilage explants

21 January 2018

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Accelerated, aging-dependent development of osteoarthritis in alpha1 integrin-deficient mice

21 January 2018

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Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice

21 January 2018

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Immature murine articular chondrocytes in primary culture: a new tool for investigating cartilage

21 January 2018

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Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes

21 January 2018

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Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage.

21 January 2018

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Effects of spermine and sodium butyrate on the in vitro phosphorylation of HMG non-histone proteins of the liver of young and old rats.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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27 November 2018

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12 December 2020

Osteoarthritis-like changes and decreased mechanical function of articular cartilage in the joints of mice with the chondrodysplasia gene (cho)

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12 December 2020

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0806062106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19139395%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

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19 January 2020

2 references

24 January 2017