Chfr is required for tumor suppression and Aurora A regulation (Q28510913)

GOA release 2020-03-11

Aurora kinase A

1 reference

GOA release 2020-03-11

10

Jan van Deursen

1 reference

25 January 2017

Xiaochun Yu

1

1 reference

25 January 2017

Katherine Minter-Dykhouse

2

1 reference

25 January 2017

Liviu Malureanu

3

1 reference

25 January 2017

Wei-Meng Zhao

4

1 reference

25 January 2017

Dongwei Zhang

5

1 reference

25 January 2017

Carolin J. Merkle

6

1 reference

25 January 2017

Irene M. Ward

7

1 reference

25 January 2017

Hideyuki Saya

8

1 reference

25 January 2017

Guowei Fang

9

1 reference

25 January 2017

Junjie Chen

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

11

1 reference

25 January 2017

language of work or name

English

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publication date

1 April 2005

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25 January 2017

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25 January 2017

37

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25 January 2017

401–406

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25 January 2017

4

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25 January 2017

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Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

21 April 2017

1 reference

Mutations of mitotic checkpoint genes in human cancers

21 April 2017

1 reference

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

21 April 2017

1 reference

Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells

21 April 2017

1 reference

The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition

21 April 2017

1 reference

The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains

21 April 2017

1 reference

CHFR-associated early G2/M checkpoint defects in breast cancer cells

21 April 2017

1 reference

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

21 April 2017

1 reference

Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer

21 April 2017

1 reference

Frequent hypermethylation of the 5' CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer

21 April 2017

1 reference

Epigenetic inactivation of CHFR in human tumors

21 April 2017

1 reference

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

21 April 2017

1 reference

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

21 April 2017

1 reference

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 April 2017

1 reference

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 April 2017

1 reference

The cellular geography of aurora kinases

21 April 2017

1 reference

The Aurora kinases: role in cell transformation and tumorigenesis

21 April 2017

1 reference

Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.

21 January 2018

1 reference

Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

21 January 2018

1 reference

The Spindle Assembly and Spindle Position Checkpoints

21 January 2018

1 reference

Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers.

21 January 2018

1 reference

Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate

21 January 2018

1 reference

Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN)

21 January 2018

1 reference