High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading (Q28510929)

GOA release 2020-03-11

author name string

Robert E. Goldsby

1

1 reference

25 January 2017

Laura E. Hays

2

1 reference

25 January 2017

Xin Chen

3

1 reference

25 January 2017

Elise A. Olmsted

4

1 reference

25 January 2017

William B. Slayton

5

1 reference

25 January 2017

Gerry J. Spangrude

6

1 reference

25 January 2017

Bradley D. Preston

Proceedings of the National Academy of Sciences of the United States of America

7

1 reference

25 January 2017

language of work or name

English

0 references

publication date

26 November 2002

1 reference

25 January 2017

1 reference

25 January 2017

99

1 reference

25 January 2017

15560–15565

1 reference

25 January 2017

24

1 reference

25 January 2017

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Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines

19 March 2017

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Mouse DNA polymerase delta gene (Pold1) maps to chromosome 7

19 March 2017

1 reference

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DNA polymerase delta, an essential enzyme for DNA transactions

19 March 2017

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Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice

19 March 2017

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Pathway correcting DNA replication errors in Saccharomyces cerevisiae

19 March 2017

1 reference

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Polymerase delta variants in RER colorectal tumours

19 March 2017

1 reference

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Further studies on calf thymus DNA polymerase delta purified to homogeneity by a new procedure

19 March 2017

1 reference

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Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene

19 March 2017

1 reference

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Characterization of human DNA polymerase delta and its immunochemical relationships with DNA polymerase alpha and epsilon

19 March 2017

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

19 March 2017

1 reference

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

7 April 2017

1 reference

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7 April 2017

DNA replication fidelity

1 reference

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Error-prone repair DNA polymerases in prokaryotes and eukaryotes

7 April 2017

1 reference

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The selection for mismatch repair defects in hereditary nonpolyposis colorectal cancer: revising the mutator hypothesis.

29 September 2017

1 reference

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DNA polymerase eta undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mre11-dependent recombination

29 September 2017

1 reference

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A mutator phenotype in cancer.

29 September 2017

1 reference

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Cutaneous squamous-cell carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137756

Deficient DNA mismatch repair: a common etiologic factor for colon cancer

29 September 2017

1 reference

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Spontaneous DNA damage, genome instability, and cancer--when DNA replication escapes control.

29 September 2017

1 reference

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Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137756

The role of mismatch repair in DNA damage-induced apoptosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137756

Common pathways for ultraviolet skin carcinogenesis in the repair and replication defective groups of xeroderma pigmentosum

29 September 2017

1 reference

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Mammalian DNA mismatch repair

29 September 2017

1 reference

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Mouse models for colorectal cancer

29 September 2017

1 reference

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29 September 2017

1 reference

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Epithelial carcinogenesis in the mouse: correlating the genetics and the biology

29 September 2017

1 reference

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Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137756

Regulation of DNA metabolic enzymes upon induction of preB cell development and V(D)J recombination: up-regulation of DNA polymerase delta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137756

The mutation rate and cancer

29 September 2017

1 reference

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Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice.

29 September 2017

1 reference

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Intrathymic maturation of murine T lymphocytes from CD8+ precursors

29 September 2017

1 reference

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Longevity, body weight, and neoplasia in ad libitum-fed and diet-restricted C57BL6 mice fed NIH-31 open formula diet

29 September 2017

1 reference

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A table for the estimation of the spontaneous mutations rate of cells in culture

2 June 2018

1 reference

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Hydrolysis of 3'-terminal mispairs in vitro by the 3'----5' exonuclease of DNA polymerase delta permits subsequent extension by DNA polymerase alpha

2 June 2018

1 reference

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Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants

2 June 2018

1 reference

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Mutators in Escherichia coli

21 January 2018

1 reference

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Rhodamine-123 staining in hematopoietic stem cells of young mice indicates mitochondrial activation rather than dye efflux.

21 January 2018

1 reference

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Defects of the mismatch repair gene MSH2 are implicated in the development of murine and human lymphoblastic lymphomas and are associated with the aberrant expression of rhombotin-2 (Lmo-2) and Tal-1 (SCL).

27 November 2018

1 reference

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Non-injection methods for the production of embryonic stem cell-embryo chimaeras

27 November 2018

1 reference

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A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232340999

Structure-function analysis of 3'-->5'-exonuclease of DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232340999

Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232340999

Proofreading of DNA polymerase eta-dependent replication errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.232340999

Mutator phenotype in Msh2-deficient murine embryonic fibroblasts

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12429860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1 hybrids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12429860