Agrin and synaptic laminin are required to maintain adult neuromuscular junctions (Q28511069)

25 January 2017

title

Agrin and synaptic laminin are required to maintain adult neuromuscular junctions (English)

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25 January 2017

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GOA release 2020-03-11

neuromuscular junction

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Jeff W. Lichtman

4

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Joshua R. Sanes

series ordinal

5

object named as

Joshua R. Sanes

1 reference

25 January 2017

Melanie A. Samuel

1

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25 January 2017

Gregorio Valdez

series ordinal

2

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25 January 2017

Juan C. Tapia

series ordinal

3

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25 January 2017

language of work or name

English

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publication date

1 January 2012

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25 January 2017

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25 January 2017

volume

7

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25 January 2017

issue

10

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25 January 2017

page(s)

e46663

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Creative Commons Attribution 4.0 International

25 January 2017

copyright license

start time

3 October 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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To build a synapse: signaling pathways in neuromuscular junction assembly

19 March 2017

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LRP4 serves as a coreceptor of agrin

19 March 2017

1 reference

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Lrp4 is a receptor for Agrin and forms a complex with MuSK

19 March 2017

1 reference

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Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals

19 March 2017

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Acetylcholine receptors are required for agrin-induced clustering of postsynaptic proteins.

19 March 2017

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Induction, assembly, maturation and maintenance of a postsynaptic apparatus

19 March 2017

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Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation

19 March 2017

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Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse

19 March 2017

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Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction

19 March 2017

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Synaptic laminin prevents glial entry into the synaptic cleft

19 March 2017

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Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice

19 March 2017

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The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform

19 March 2017

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Defective neuromuscular synaptogenesis in agrin-deficient mutant mice

19 March 2017

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Agrin acts via a MuSK receptor complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

19 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin beta 2

19 March 2017

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Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

19 March 2017

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

7 April 2017

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Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Shared resistance to aging and ALS in neuromuscular junctions of specific muscles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Specific proteolytic cleavage of agrin regulates maturation of the neuromuscular junction

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Antibody effector mechanisms in myasthenia gravis-pathogenesis at the neuromuscular junction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Single-neuron labeling with inducible Cre-mediated knockout in transgenic mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Agrin promotes synaptic differentiation by counteracting an inhibitory effect of neurotransmitter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Laminin functions in tissue morphogenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Activity dependent removal of agrin from synaptic basal lamina by matrix metalloproteinase 3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

The basement membrane/basal lamina of skeletal muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Effects of purified recombinant neural and muscle agrin on skeletal muscle fibers in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

29 September 2017

Motor nerve sprouting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

MuSK controls where motor axons grow and form synapses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Synapse disassembly and formation of new synapses in postnatal muscle upon conditional inactivation of MuSK.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Active zones on motor nerve terminals contain alpha 3beta 1 integrin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Developmental regulation of highly active alternatively spliced forms of agrin

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Brain extract induces synaptic characteristics in the basal lamina of cultured myotubes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Endurance exercise alters the morphology of fast- and slow-twitch rat neuromuscular junctions

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Neuromuscular junctions shrink and expand as muscle fiber size is manipulated: in vivo observations in the androgen-sensitive bulbocavernosus muscle of mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Repeated in vivo visualization of neuromuscular junctions in adult mouse lateral gastrocnemius.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Effects of long-term denervation on the rat thyroarytenoid muscle

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Increased and decreased activity elicits specific morphological adaptations of the neuromuscular junction

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Proteolytic processing of the laminin alpha3 G domain mediates assembly of hemidesmosomes but has no role on keratinocyte migration

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Neuromuscular synapses can form in vivo by incorporation of initially aneural postsynaptic specializations

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Mapping sites responsible for interactions of agrin with neurons

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Ultrastructural studies of young and old mouse neuromuscular junctions.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463559

Scanning and light microscopic study of age changes at a neuromuscular junction in the mouse

27 November 2018

1 reference

12 December 2020

Aging rat neuromuscular junctions: a morphometric study of cholinesterase-stained whole mounts and ultrastructure

1 reference

12 December 2020

Visualization of neuromuscular junctions over periods of several months in living mice

1 reference

12 December 2020

In vivo visualization of the growth of pre- and postsynaptic elements of neuromuscular junctions in the mouse

1 reference

12 December 2020

1 reference

12 December 2020

Evidence that agrin directly influences presynaptic differentiation at neuromuscular junctions in vitro

1 reference

12 December 2020

A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4

1 reference

12 December 2020

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

12 December 2020

Destabilization of the neuromuscular junction by proteolytic cleavage of agrin results in precocious sarcopenia

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0046663

Identifiers

DOI

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ADS bibcode

2012PLoSO...746663S

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1 reference

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