Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival (Q28511090)

25 January 2017

title

Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival (English)

1 reference

Vascular endothelial growth factor A

25 January 2017

main subject

1 reference

GOA release 2020-03-11

6

Peter Carmeliet

1 reference

25 January 2017

Christa Maes

1

1 reference

25 January 2017

Ingrid Stockmans

2

1 reference

25 January 2017

Karen Moermans

3

1 reference

25 January 2017

Riet Van Looveren

4

1 reference

25 January 2017

Nico Smets

5

1 reference

25 January 2017

Roger Bouillon

7

1 reference

25 January 2017

Geert Carmeliet

8

1 reference

25 January 2017

language of work or name

English

0 references

publication date

1 January 2004

1 reference

Journal of Clinical Investigation

25 January 2017

published in

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25 January 2017

volume

113

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25 January 2017

issue

2

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25 January 2017

page(s)

188–199

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VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding

25 January 2017

cites work

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Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival

19 March 2017

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Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells

19 March 2017

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The splice variants of vascular endothelial growth factor (VEGF) and their receptors

19 March 2017

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Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family

19 March 2017

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HIF-1: mediator of physiological and pathophysiological responses to hypoxia

19 March 2017

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

19 March 2017

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MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

19 March 2017

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

19 March 2017

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Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development

19 March 2017

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Developmental regulation of the growth plate

19 March 2017

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Mechanisms of angiogenesis and arteriogenesis

7 April 2017

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Reaching a genetic and molecular understanding of skeletal development

7 April 2017

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Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis

29 September 2017

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Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

29 September 2017

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The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis

29 September 2017

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Semaphorin 3A-vascular endothelial growth factor-165 balance mediates migration and apoptosis of neural progenitor cells by the recruitment of shared receptor.

29 September 2017

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Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts

29 September 2017

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Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

29 September 2017

1 reference

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Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165.

29 September 2017

1 reference

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Semaphorin III is needed for normal patterning and growth of nerves, bones and heart

29 September 2017

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The role of the epiphyseal and metaphyseal circulations on longitudinal growth in the dog: an experimental study

29 September 2017

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Vascular events associated with the appearance of the secondary center of ossification in the murine distal femoral epiphysis

29 September 2017

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Structure and function of the growth plate

29 September 2017

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VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

29 September 2017

1 reference

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Perivascular cells in cartilage canals of the developing mouse epiphysis

2 June 2018

1 reference

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HIF-1alpha controls extracellular matrix synthesis by epiphyseal chondrocytes

2 June 2018

1 reference

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VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

27 November 2018

1 reference

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VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition

27 November 2018

1 reference

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Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

27 November 2018

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Structural stages in the development of the long bones and epiphyses: a study in the New Zealand white rabbit

27 November 2018

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Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

27 November 2018

1 reference

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Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state.

27 November 2018

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Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs.

27 November 2018

1 reference

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The blood supply of the growth plate and the epiphysis: a comparative scanning electron microscopy and histological experimental study in growing sheep

27 November 2018

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12 December 2020

Experience with latrogenic pediatric vascular injuries. Incidence, etiology, management, and results

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12 December 2020

MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

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12 December 2020

EPIPHYSEAL AVASCULAR NECROSIS AND ITS RELATION TO LONGITUDINAL BONE GROWTH

1 reference

12 December 2020

The vascular contribution to osteogenesis. III. Changes in the growth cartilage caused by experimentally induced ischaemia

1 reference

12 December 2020

Diminished epiphyseal growth following iatrogenic vascular trauma

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12 December 2020

Identifiers

DOI

10.1172/JCI19383

1 reference

1 reference

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