HNF1alpha is involved in tissue-specific regulation of CFTR gene expression (Q28511513)

25 January 2017

title

HNF1alpha is involved in tissue-specific regulation of CFTR gene expression (English)

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25 January 2017

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GOA release 2020-03-11

HNF1 homeobox A

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GOA release 2020-03-11

author name string

Nathalie Mouchel

1

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25 January 2017

Sytse A. Henstra

2

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25 January 2017

Victoria A. McCarthy

3

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25 January 2017

Sarah H. Williams

4

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25 January 2017

Marios Phylactides

5

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25 January 2017

Ann Harris

6

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25 January 2017

language of work or name

English

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publication date

15 March 2004

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25 January 2017

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25 January 2017

volume

378

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25 January 2017

issue

Pt 3

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25 January 2017

page(s)

909–918

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Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences

25 January 2017

cites work

1 reference

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Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets

19 March 2017

1 reference

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Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins

19 March 2017

1 reference

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Regulation of alpha1-antitrypsin gene expression in human intestinal epithelial cell line caco-2 by HNF-1alpha and HNF-4

19 March 2017

1 reference

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Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

19 March 2017

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

19 March 2017

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TRANSFAC: an integrated system for gene expression regulation

19 March 2017

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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

7 April 2017

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FGFR4 overexpression in pancreatic cancer is mediated by an intronic enhancer activated by HNF1alpha

7 April 2017

1 reference

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A transcription factor regulatory circuit in differentiated pancreatic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

An element in intron 1 of the CFTR gene augments intestinal expression in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Regulation of the human Na(+)-glucose cotransporter gene, SGLT1, by HNF-1 and Sp1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Overexpression of pterin-4a-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 in human colon cancer

29 September 2017

1 reference

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Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells.

29 September 2017

1 reference

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Characterization of the aldolase B intronic enhancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Hepatocyte nuclear factor 1alpha gene inactivation impairs chromatin remodeling and demethylation of the phenylalanine hydroxylase gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Characterization of the cAMP response element of the cystic fibrosis transmembrane conductance regulator gene promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

A regulatory element in intron 1 of the cystic fibrosis transmembrane conductance regulator gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Basal expression of the cystic fibrosis transmembrane conductance regulator gene is dependent on protein kinase A activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Transcription of cystic fibrosis transmembrane conductance regulator requires a CCAAT-like element for both basal and cAMP-mediated regulation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

A human cell line from a pleural effusion derived from a breast carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

The cystic fibrosis gene has a "housekeeping"-type promoter and is expressed at low levels in cells of epithelial origin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Analysis of a DNase I hypersensitive site located -20.9 kb upstream of the CFTR gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Expression of the cystic fibrosis gene and the major pancreatic mucin gene, MUC1, in human ductal epithelial cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Characterization of the cystic fibrosis transmembrane conductance regulator promoter region. Chromatin context and tissue-specificity.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Characterization of DNASE I hypersensitive sites in the 120kb 5' to the CFTR gene

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Lymphocyte mRNA as a resource for detection of mutations and polymorphisms in the CF gene

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Absence of HeLa cell contamination in 169 cell lines derived from human tumors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Alternative 5' exons of the CFTR gene show developmental regulation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Evaluation of potential regulatory elements identified as DNase I hypersensitive sites in the CFTR gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

The sheep genome contributes to localization of control elements in a human gene with complex regulatory mechanisms

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1224019

Multiple potential intragenic regulatory elements in the CFTR gene

27 November 2018

1 reference

12 December 2020

A comparative genomic analysis of the cow, pig, and human CFTR genes identifies potential intronic regulatory elements

1 reference

12 December 2020

The alpha 1-antitrypsin gene is expressed in a human intestinal epithelial cell line

1 reference

12 December 2020

Transcriptional repression of the cystic fibrosis transmembrane conductance regulator gene, mediated by CCAAT displacement protein/cut homolog, is associated with histone deacetylation

1 reference

12 December 2020

CFTR expression does not influence glycosylation of an epitope-tagged MUC1 mucin in colon carcinoma cell lines

1 reference

12 December 2020

Induction of expression of the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

Expression of the cystic fibrosis gene in human foetal tissues

1 reference

12 December 2020

HNF-1 alpha and HNF-1 beta expression in mouse intestinal crypts

1 reference

12 December 2020

A naturally occurring sequence variation that creates a YY1 element is associated with increased cystic fibrosis transmembrane conductance regulator gene expression

1 reference

12 December 2020

Identifiers

1 reference

25 January 2017

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