AP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signaling (Q28511741)

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1 February 2020

title

AP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signaling (English)

2 references

25 January 2017

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1 February 2020

1 reference

GOA release 2020-03-11

author

Toshinori Nakayama

6

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author name string

Masashi Watanabe

1

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1 February 2020

Shinsuke Nakajima

2

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1 February 2020

Kazunobu Ohnuki

3

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1 February 2020

Shuhei Ogawa

4

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1 February 2020

Masakatsu Yamashita

5

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1 February 2020

Yasufumi Murakami

7

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1 February 2020

Kazunari Tanabe

8

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Ryo Abe

9

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language of work or name

English

0 references

publication date

1 July 2012

2 references

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European Journal of Immunology

1 February 2020

published in

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volume

42

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issue

7

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page(s)

1850-1862

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The role of the CD28 receptor during T cell responses to antigen

1 February 2020

cites work

1 reference

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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

21 January 2018

1 reference

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T-cell co-stimulation through B7RP-1 and ICOS

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ICOS is critical for CD40-mediated antibody class switching

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ICOS is essential for effective T-helper-cell responses

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Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

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Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA

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Expression level of costimulatory receptor ICOS is critical for determining the polarization of helper T cell function.

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Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production

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Expression and function of inducible costimulator on peripheral blood T cells in patients with systemic lupus erythematosus.

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Fos/AP-1 proteins in bone and the immune system

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A distinct role for ICOS-mediated co-stimulatory signaling in CD4+ and CD8+ T cell subsets.

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Dominant-negative effect of the c-fos family gene products on inducible NO synthase expression in macrophages

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MAP kinases in the immune response

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Protein kinase C(theta) in T cell activation

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Transcription factors of the NFAT family: regulation and function

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A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)

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ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells

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Gamma c cytokines condition the progressive differentiation of CD4+ T cells

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IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

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The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

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Plat-E: an efficient and stable system for transient packaging of retroviruses

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Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor

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Cyclic adenosine monophosphate suppresses the transcription of proinflammatory cytokines via the phosphorylated c-Fos protein

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JUN siRNA regulates matrix metalloproteinase-2 expression, microvascular endothelial growth and retinal neovascularisation

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Targeting c-Jun and JunB proteins as potential anticancer cell therapy

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Transcriptional repression of ATP-binding cassette transporter A1 gene in macrophages: a novel atherosclerotic effect of angiotensin II.

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Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene

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ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses

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Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells

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T helper cell-specific regulation of inducible costimulator expression via distinct mechanisms mediated by T-bet and GATA-3

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7 January 2021

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AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

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Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells

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7 January 2021

ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling

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7 January 2021

Identifiers

DOI

10.1002/EJI.201141897

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22585681%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22585681%20AND%20SRC:MED&resulttype=core&format=json