Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice (Q28511888)

Hypoxanthine guanine phosphoribosyl transferase

GOA release 2020-03-11

1 reference

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

GOA release 2020-03-11

author name string

C. L. Wu

series ordinal

1

1 reference

25 January 2017

D. W. Melton

series ordinal

2

1 reference

25 January 2017

language of work or name

English

0 references

publication date

1 March 1993

1 reference

25 January 2017

1 reference

25 January 2017

20 April 2017

volume

3

1 reference

25 January 2017

3

1 reference

25 January 2017

235–240

1 reference

25 January 2017

1 reference

https://api.crossref.org/works/10.1038/NG0393-235

A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/NG0393-235

Amphetamine-induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/NG0393-235

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Effects of an Rb mutation in the mouse

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

A FAMILIAL DISORDER OF URIC ACID METABOLISM AND CENTRAL NERVOUS SYSTEM FUNCTION

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Biochemical Evidence of Dysfunction of Brain Neurotransmitters in the Lesch-Nyhan Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

A dopamine deficiency model of Lesch-Nyhan disease--the neonatal-6-OHDA-lesioned rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Animal models of Lesch-Nyhan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Monoamine deficiency in a transgenic (Hprt-) mouse model of Lesch-Nyhan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Profiles of hypoxanthine guanine phosphoribosyl transferase and adenine phosphoribosyl transferase activities measured in single preimplantation human embryos by high-performance liquid chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Cystic fibrosis in the mouse by targeted insertional mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Requirement for a functional Rb-1 gene in murine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Chronic methylxanthine treatment in rats: A comparison of Wistar and Fischer 344 strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

Identification of a single nucleotide change in the hypoxanthine-guanine phosphoribosyltransferase gene (HPRTYale) responsible for Lesch-Nyhan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Identification of mutations leading to the Lesch-Nyhan syndrome by automated direct DNA sequencing of in vitro amplified cDNA.

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Biochemical basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in nine families

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Lesch-Nyhan syndrome: molecular investigation of three French Canadian families using a hypoxanthine-guanine phosphoribosyltransferase cDNA probe

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Lesch-Nyhan syndrome: low dopamine-beta-hydroxylase activity and diminished sympathetic response to stress and posture

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Self-injurious behavior produced in rats by daily caffeine and continuous amphetamine

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Lesch-Nyhan Syndrome, Caffeine Model: Increase of Purine and Pyrimidine Enzymes in Rat Brain

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Possible Involvement of a Central Noradrenergic System in Automutilation Induced by Clonidine in Mice

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Involvement of adenosine receptor activities in aggressive responses produced by clonidine in mice

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Mouse models of hypoxanthine phosphoribosyltransferase deficiency

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Salvage of circulating hypoxanthine by tissues of the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Developmental changes in the activity of enzymes of purine metabolism in rat neuronal cells in culture and in whole brain

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Inherited disorder of purine metabolism. Correlation between central nervous system dysfunction and biochemical defects

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Genetics of human cess line. IV. DNA-mediated heritable transformation of a biochemical trait

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Analysis of forebrain dopaminergic pathways in HPRT-mice

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

An observational method for quantifying the behavioural effects of dopamine agonists: Contrasting effects of d-Amphetamine and apomorphine

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

A computer-supported method for analyzing behavioral observations: studies with stereotypy

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

X chromosome-linked muscular dystrophy (mdx) in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

An animal model for cystic fibrosis made by gene targeting

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

2,8-Dihydroxyadenine lithiasis

1 reference

https://api.crossref.org/works/10.1038%2FNG0393-235

7 January 2021

Identifiers

DOI

10.1038/NG0393-235

1 reference

Consolidated OpenCitations Corpus – April 2017

1600907

1600907

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference