Xanthine oxidoreductase is central to the evolution and function of the innate immune system (Q28512767)

Identification of two mutations in human xanthine dehydrogenase gene responsible for classical type I xanthinuria

GOA release 2020-03-11

author name string

Claudia Vorbach

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1

1 reference

25 January 2017

Roger Harrison

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2

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25 January 2017

Mario R. Capecchi

series ordinal

3

1 reference

25 January 2017

1 September 2003

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25 January 2017

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25 January 2017

24

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25 January 2017

512–517

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25 January 2017

9

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25 January 2017

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https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Structure and function of xanthine oxidoreductase: where are we now?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

The physiology of endothelial xanthine oxidase: from urate catabolism to reperfusion injury to inflammatory signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Allantoin as a free-radical scavenger

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Free radicals in the physiological control of cell function

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Mammalian molybdo-flavoenzymes, an expanding family of proteins: structure, genetics, regulation, function and pathophysiology

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Towards the physiological function of uric acid

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Marked elevation in cortical urate and xanthine oxidoreductase activity in experimental bacterial meningitis

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https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Characterization of the differentiated antioxidant profile of human saliva

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Free radicals and phagocytic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Antimicrobial properties of milk: dependence on presence of xanthine oxidase and nitrite

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Reactive oxygen species and antimicrobial defenses of invertebrates: a bivalve model

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase

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https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

The comparative toxicity of nitric oxide and peroxynitrite to Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Cytotoxic reactions associated with insect immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Xanthine oxidase catalyzes the synthesis of retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

High levels of xanthine oxidoreductase in rat endothelial, epithelial and connective tissue cells. A relation between localization and function?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Tissue- and cell-specific expression of mouse xanthine oxidoreductase gene in vivo: regulation by bacterial lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Uric acid is a major antioxidant in human nasal airway secretions

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Experimental meningitis in the rat: protection by uric acid at human physiological blood concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Uric acid as radical scavenger and antioxidant in the heart.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Pulmonary microvascular endothelial cells constitutively release xanthine oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Immunoaffinity localization of the enzyme xanthine oxidase on the outside surface of the endothelial cell plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Xanthine oxidoreductase is asymmetrically localised on the outer surface of human endothelial and epithelial cells in culture.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Histochemical localization and possible antibacterial role of xanthine oxidase in the bovine mammary gland.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Antibacterial properties of xanthine oxidase in human milk.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Identification of xanthine dehydrogenase/xanthine oxidase as a rat Paneth cell zinc-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Evidence implicating xanthine oxidase and neutrophils in reperfusion-induced microvascular dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Rapid upregulation of endothelial P-selectin expression via reactive oxygen species generation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

The Toll-receptor family and control of innate immunity

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https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

NF-kappaB signaling pathways in mammalian and insect innate immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH).

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Upregulation of xanthine oxidase by lipopolysaccharide, interleukin-1, and hypoxia. Role in acute lung injury.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Regulation of the transcription factors NF-kappa B and AP-1 by redox changes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

1 reference

7 January 2021

Xanthine oxidase-derived reactive oxygen species activate nuclear factor kappa B during hepatic ischemia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Nitric oxide suppresses IL-8 transcription by inhibiting c-Jun N-terminal kinase-induced AP-1 activation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Serum xanthine oxidase: origin, regulation, and contribution to control of trypanosome parasitemia

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Complement activation by the hydroxyl radical during intestinal reperfusion.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Free radicals upregulate complement expression in rabbit isolated heart

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Quantitative discrimination of hepatic reticuloendothelial clearance and phagocytic killing.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Liver xanthine oxidase increase in mice in three patholgoical models. A possible defence mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Allopurinol: discrimination of antioxidant from enzyme inhibitory activities

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Endothelial cells potentiate oxidant-mediated Kupffer cell phagocytic killing.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Molecular signatures of sepsis: multiorgan gene expression profiles of systemic inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Liver xanthine oxidase activity of mice infected with Schistosoma mansoni

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Xanthine oxidase increase in polymorphonuclear leucocytes and macrophages in mice in three pathological situations.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Role of reactive oxygen metabolites in murine peritoneal macrophage phagocytosis and phagocytic killing

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Xanthine oxidase contributes to host defense against Burkholderia cepacia in the p47(phox-/-) mouse model of chronic granulomatous disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

The instructive role of innate immunity in the acquired immune response

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https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Insect hemocytes and their role in immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Nitric oxide involvement in Drosophila immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Uric acid content of Drosophila decreases with aging

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Molecular cloning and chromosomal localization of a prophenoloxidase cDNA from the malaria vector Anopheles gambiae

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Role of the prophenoloxidase-activating system in invertebrate immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

The antimicrobial properties of melanocytes, melanosomes and melanin and the evolution of black skin

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Evolution of supergene families associated with insecticide resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Molecular characterization of the amplified aldehyde oxidase from insecticide resistant Culex quinquefasciatus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Phylogeny and correlations of aldehyde oxidase, xanthine oxidase, xanthine dehydrogenase and peroxidase in animal tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Innate immunity and the normal microflora

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021

Phosphorylation of xanthine dehydrogenase/oxidase in hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2803%2900237-0

7 January 2021