γ-Hydroxybutyric acid (GHB) is not an agonist of extrasynaptic GABAA receptors (Q28535012)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

γ-Hydroxybutyric acid (GHB) is not an agonist of extrasynaptic GABAA receptors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1

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1 March 2020

Adam Errington

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Vincenzo Crunelli

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Vincenzo Crunelli

series ordinal

3

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language of work or name

English

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publication date

11 November 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

11

1 reference

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1 March 2020

page(s)

e79062

1 reference

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Creative Commons Attribution 4.0 International

1 March 2020

copyright license

start time

11 November 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3823990/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

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GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

19 March 2017

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Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors

19 March 2017

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Adjacent phosphorylation sites on GABAA receptor beta subunits determine regulation by cAMP-dependent protein kinase

19 March 2017

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The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

19 March 2017

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Failure of gamma-hydroxybutyrate to alter the function of the GABAA receptor complex in the rat cerebral cortex

19 March 2017

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Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

19 March 2017

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GABAB Receptors Regulate Extrasynaptic GABAA Receptors.

7 April 2017

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Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain.

29 September 2017

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Extrasynaptic GABA(A) receptors: their function in the CNS and implications for disease

29 September 2017

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Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid

29 September 2017

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Developmental regulation and neuroprotective effects of striatal tonic GABAA currents

29 September 2017

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Modulation of spontaneous and GABA-evoked tonic alpha4beta3delta and alpha4beta3gamma2L GABAA receptor currents by protein kinase A.

29 September 2017

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29 September 2017

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Effects of gamma hydroxybutyric acid on inhibition and excitation in rat neocortex

29 September 2017

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Novel cyclic gamma-hydroxybutyrate (GHB) analogs with high affinity and stereoselectivity of binding to GHB sites in rat brain.

29 September 2017

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Comparison of the behavioral effects of gamma-hydroxybutyric acid (GHB) and its 4-methyl-substituted analog, gamma-hydroxyvaleric acid (GHV).

29 September 2017

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From the street to the brain: neurobiology of the recreational drug gamma-hydroxybutyric acid

29 September 2017

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Pathway-specific action of gamma-hydroxybutyric acid in sensory thalamus and its relevance to absence seizures.

29 September 2017

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Perisynaptic localization of delta subunit-containing GABA(A) receptors and their activation by GABA spillover in the mouse dentate gyrus.

29 September 2017

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Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors

29 September 2017

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Cloning and characterization of a rat brain receptor that binds the endogenous neuromodulator gamma-hydroxybutyrate (GHB).

29 September 2017

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Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist

29 September 2017

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The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

29 September 2017

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Identification of endogenous gamma-hydroxybutyrate in human and bovine brain and its regional distribution in human, guinea pig and rhesus monkey brain

29 September 2017

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Effects of GABA agonists on body temperature regulation in GABA(B(1))-/- mice

29 September 2017

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GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

20 June 2018

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Gamma-hydroxybutyric acid decreases thalamic sensory excitatory postsynaptic potentials by an action on presynaptic GABAB receptors

20 June 2018

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γ-Hydroxybutyric acid binding sites: Interaction with the GABA-benzodiazepine-picrotoxin receptor complex

20 June 2018

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Gamma hydroxybutyrate. Correlation of serum and cerebrospinal fluid levels with electroencephalographic and behavioral effects

20 June 2018

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Gamma-aminobutyric acidB (GABAB)-receptor mediation of different in vivo effects of gamma-butyrolactone

20 June 2018

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Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice

21 January 2018

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GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice.

21 January 2018

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gamma-hydroxybutyrate increases a potassium current and decreases the H-current in hippocampal neurons via GABAB receptors

21 January 2018

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Presynaptic modulation of spontaneous inhibitory postsynaptic currents by gamma-hydroxybutyrate in the substantia nigra pars compacta

21 January 2018

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GHB depresses fast excitatory and inhibitory synaptic transmission via GABA(B) receptors in mouse neocortical neurons

21 January 2018

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gamma-Hydroxybutyric acid binding sites: evidence for coupling to a chloride anion channel

21 January 2018

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Gamma-hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors.

21 January 2018

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gamma-Hydroxybutyrate (GHB) induces GABA(B) receptor independent intracellular Ca2+ transients in astrocytes, but has no effect on GHB or GABA(B) receptors of medium spiny neurons in the nucleus accumbens.

21 January 2018

1 reference

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Differential tonic GABA conductances in striatal medium spiny neurons

21 January 2018

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GABAA receptor-mediated tonic inhibition in thalamic neurons.

21 January 2018

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Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics.

21 January 2018

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The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells.

21 January 2018

1 reference

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Binding characteristics of the gamma-hydroxybutyric acid receptor antagonist [(3)H](2E)-(5-hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid in the rat brain

21 January 2018

1 reference

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Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24244421

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0079062

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

24244421

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24244421%20AND%20SRC:MED&resulttype=core&format=json