Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma (Q28539182)

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scientific article (publication date: 2014)

Language	Label	Description	Also known as
English	Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma	scientific article (publication date: 2014)

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scholarly article

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Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma (English)

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ChEBI release 2020-05-28

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based on heuristic

inferred from title

colorectal adenocarcinoma

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based on heuristic

inferred from title

author name string

Feng-Hsiang Chung

1

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Yun-Ru Chiang

2

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Ai-Lun Tseng

3

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Yung-Chuan Sung

4

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Jean Lu

5

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Min-Chang Huang

6

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Nianhan Ma

7

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Hoong-Chien Lee

8

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language of work or name

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publication date

2014

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9

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1

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e86299

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copyright license

Creative Commons Attribution 4.0 International

27 January 2014

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April 2022 Public Data File from Crossref

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describes a project that uses

object named as

limma

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Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3903539

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1 reference

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1 reference

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1 reference

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[Clinical investigations of 6-azathymine: a thymine analog.]

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1 reference

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Identifiers

10.1371/JOURNAL.PONE.0086299

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2014PLoSO...986299C

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Consolidated OpenCitations Corpus – April 2017

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PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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