Hydroxytyrosol prevents increase of osteoarthritis markers in human chondrocytes treated with hydrogen peroxide or growth-related oncogene α (Q28543546)

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English	Hydroxytyrosol prevents increase of osteoarthritis markers in human chondrocytes treated with hydrogen peroxide or growth-related oncogene α	scientific article

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20 February 2020

Hydroxytyrosol prevents increase of osteoarthritis markers in human chondrocytes treated with hydrogen peroxide or growth-related oncogene α (English)

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20 February 2020

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Stefania D'Adamo

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20 February 2020

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Annalisa Facchini

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20 February 2020

Silvia Cetrullo

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20 February 2020

Serena Guidotti

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20 February 2020

Manuela Minguzzi

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20 February 2020

Andrea Facchini

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20 February 2020

Rosa Maria Borzì

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20 February 2020

Flavio Flamigni

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3 October 2014

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20 February 2020

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20 February 2020

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20 February 2020

e109724

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20 February 2020

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20 February 2020

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Creative Commons Attribution 4.0 International

3 October 2014

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Redox regulation of SIRT1 in inflammation and cellular senescence

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Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents

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19 March 2017

Further evidence for the anti-inflammatory activity of oleocanthal: inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes

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19 March 2017

Effect of oleocanthal and its derivatives on inflammatory response induced by lipopolysaccharide in a murine chondrocyte cell line

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29 September 2017

Anti-apoptotic activity of hydroxytyrosol and hydroxytyrosyl laurate

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29 September 2017

Metabolic syndrome meets osteoarthritis

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29 September 2017

Dietary polyphenols and mechanisms of osteoarthritis.

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29 September 2017

Hydroxytyrosol protects against oxidative DNA damage in human breast cells

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A diet rich in olive oil phenolics reduces oxidative stress in the heart of SAMP8 mice by induction of Nrf2-dependent gene expression.

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29 September 2017

Hydroxytyrosol is the major anti-inflammatory compound in aqueous olive extracts and impairs cytokine and chemokine production in macrophages

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29 September 2017

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29 September 2017

Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.

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29 September 2017

Regulation of SIRT1 in cellular functions: role of polyphenols

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29 September 2017

Hydroxytyrosol: from laboratory investigations to future clinical trials.

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29 September 2017

Mechanism of elimination of phosphorylated histone H2AX from chromatin after repair of DNA double-strand breaks

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29 September 2017

The protective effects of hydroxytyrosol against UVB-induced DNA damage in HaCaT cells

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29 September 2017

Suppressive effects of hydroxytyrosol on oxidative stress and nuclear Factor-kappaB activation in THP-1 cells

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29 September 2017

Growth plate cartilage as developmental model in osteoarthritis research--potentials and limitations

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29 September 2017

Polyamine depletion inhibits apoptosis following blocking of survival pathways in human chondrocytes stimulated by tumor necrosis factor-alpha

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29 September 2017

Hydrolyzed olive vegetation water in mice has anti-inflammatory activity

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29 September 2017

Chemokines in cartilage degradation

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Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: a potentially protective mechanism in atherosclerotic vascular disease and cancer

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3 June 2018

Matrix metalloproteinase 13 loss associated with impaired extracellular matrix remodeling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factors

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3 June 2018

Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells

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3 June 2018

Differential requirements for IKKalpha and IKKbeta in the differentiation of primary human osteoarthritic chondrocytes.

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3 June 2018

Phase 2 enzyme inducer sulphoraphane blocks matrix metalloproteinase production in articular chondrocytes.

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Phase 2 enzyme inducer sulphoraphane blocks prostaglandin and nitric oxide synthesis in human articular chondrocytes and inhibits cartilage matrix degradation.

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Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo

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Hydroxytyrosol induces proliferation and cytoprotection against oxidative injury in vascular endothelial cells: role of Nrf2 activation and HO-1 induction.

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Hydroxytyrosol reduces intracellular reactive oxygen species levels in vascular endothelial cells by upregulating catalase expression through the AMPK-FOXO3a pathway

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Hydroxytyrosol, the phenolic compound of olive oil protects human PBMC against oxidative stress and DNA damage mediated by 2,3,7,8-TCDD.

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Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells.

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21 January 2018

Does white wine qualify for French paradox? Comparison of the cardioprotective effects of red and white wines and their constituents: resveratrol, tyrosol, and hydroxytyrosol

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21 January 2018

Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol

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Sulforaphane protects human chondrocytes against cell death induced by various stimuli

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Chondrocyte hypertrophy and apoptosis induced by GROalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B.

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Oleuropein aglycone, an olive oil compound, ameliorates development of arthritis caused by injection of collagen type II in mice

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Extra-virgin olive oil diet and mild physical activity prevent cartilage degeneration in an osteoarthritis model: an in vivo and in vitro study on lubricin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/25279550

12 December 2020

based on heuristic

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Osteoarthritis or osteoarthrosis: the definition of inflammation becomes a semantic issue in the genomic era of molecular medicine

1 reference

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12 December 2020

based on heuristic

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10.1371/JOURNAL.PONE.0109724

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20 February 2020

2014PLoSO...9j9724F

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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20 February 2020

2 references

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20 February 2020

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